Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.31 |
| ▸ | HTR3A | P46098 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8045519 | 0.83 | MTNR1A (0.38) | L3MBTL1TDP1 | |
| SCHEMBL8046729 | 0.82 | MTNR1A (0.39) | HTR2AHTR2CHTR2BL3MBTL1 | |
| SCHEMBL10509049 | 0.79 | L3MBTL1 (0.35) | L3MBTL1TDP1 | |
| SCHEMBL7209043 | 0.79 | L3MBTL1 (0.35) | L3MBTL1TDP1 | |
| SCHEMBL27617088 | 0.73 | L3MBTL1 (0.35) | L3MBTL1TDP1 | |
| SCHEMBL5723418 | 0.71 | L3MBTL1 (0.39) | L3MBTL1TDP1 | |
| SCHEMBL15882382 | 0.70 | L3MBTL1 (0.43) | L3MBTL1TDP1 | |
| SCHEMBL27708356 | 0.68 | L3MBTL1 (0.41) | L3MBTL1TDP1 | |
| Fluoride SCHEMBL27841384 | 0.67 | CA2 (0.47) | — | |
| SCHEMBL781788 | 0.65 | CA2 (0.48) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6100268-A | MIGRAINES | JANSSEN PHARMACEUTICA, N.V. (BE) | 2000-08-08 | — | — | US | disclosed |
| EP-0714396-A1 | VASOCONTRICTIVE DIHYDROBENZOPYRAN DERIVATIVES | JANSSEN PHARMACEUTICA N.V. (BE) | 1996-06-05 | — | — | EP | disclosed |
| WO-1995005383-A1 | VASOCONTRICTIVE DIHYDROBENZOPYRAN DERIVATIVES | JANSSEN PHARMACEUTICA N.V. (BE) | 1995-02-23 | — | — | WO | disclosed |