Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | APAF1 | O14727 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.45 |
| ▸ | FNTA | P49354 | 1/20 | 0.45 |
| ▸ | FNTB | P49356 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | BLM | P54132 | 2/20 | 0.44 |
| ▸ | MPO | P05164 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8061431 | 0.88 | KDM4E (0.45) | KDM4EMAPTAPAF1POLBRECQL | |
| SCHEMBL8061472 | 0.86 | KDM4E (0.43) | KDM4EMAPTAPAF1POLBRECQL | |
| SCHEMBL8057314 | 0.85 | DHPS (0.39) | KDM4EMAPTAPAF1POLBRECQL | |
| SCHEMBL9293379 | 0.76 | MEN1 (0.56) | KDM4EMAPTAPAF1POLBRECQL | |
| SCHEMBL8061716 | 0.75 | MTNR1A (0.43) | KDM4EMAPTSMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL343309 | 0.73 | MAPT (0.54) | KDM4EMAPTAPAF1POLBRECQL | |
| SCHEMBL29434606 | 0.73 | MAPT (0.54) | KDM4EMAPTAPAF1POLBRECQL | |
| SCHEMBL200589 | 0.73 | MAPT (0.54) | KDM4EMAPTAPAF1POLBRECQL | |
| SCHEMBL162554 | 0.73 | MAPT (0.54) | KDM4EMAPTAPAF1POLBRECQL | |
| SCHEMBL30135703 | 0.73 | MAPT (0.54) | KDM4EMAPTAPAF1POLBRECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6046180-A | NAALADase inhibitors | GUILFORD PHARMACEUTICALS INC. (US) | 2000-04-04 | — | — | US | disclosed |