Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.72 |
| ▸ | MAPT | P10636 | 3/20 | 0.72 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.72 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.72 |
| ▸ | MEN1 | O00255 | 1/20 | 0.72 |
| ▸ | GAA | P10253 | 1/20 | 0.72 |
| ▸ | HPGD | P15428 | 1/20 | 0.72 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.72 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | HTR2C | P28335 | 2/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8036213 | 0.87 | ALDH1A1 (0.53) | ALDH1A1MAPTKDM4EKMT2AMEN1 | |
| SCHEMBL8036388 | 0.85 | KMT2A (0.74) | ALDH1A1MAPTKDM4EKMT2AMEN1 | |
| SCHEMBL12048609 | 0.85 | KDM4E (0.49) | ALDH1A1MAPTKDM4EKMT2AMEN1 | |
| SCHEMBL15825184 | 0.84 | KMT2A (0.72) | ALDH1A1MAPTKDM4EKMT2AMEN1 | |
| SCHEMBL27236981 | 0.84 | KMT2A (0.72) | ALDH1A1MAPTKDM4EKMT2AMEN1 | |
| SCHEMBL18093460 | 0.83 | ALDH1A1 (0.81) | ALDH1A1MAPTKDM4EKMT2AMEN1 | |
| SCHEMBL4730776 | 0.83 | ALDH1A1 (0.70) | ALDH1A1MAPTKDM4EKMT2AMEN1 | |
| SCHEMBL8010698 | 0.82 | KMT2A (0.68) | ALDH1A1MAPTKDM4EKMT2AMEN1 | |
| SCHEMBL490810 | 0.80 | MAPT (0.70) | ALDH1A1MAPTKDM4EKMT2AMEN1 | |
| SCHEMBL17320354 | 0.80 | KDM4E (0.85) | ALDH1A1MAPTKDM4EKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8946280-B2 | Plant growth regulating compounds | SYNGENTA PARTICIPATIONS AG (CH) | 2015-02-03 | — | — | US | disclosed |
| US-8946280-B2 | Plant growth regulating compounds | SYNGENTA PARTICIPATIONS AG (CH) | 2015-02-03 | — | — | US | disclosed |
| US-8946280-B2 | Plant growth regulating compounds | SYNGENTA PARTICIPATIONS AG (CH) | 2015-02-03 | — | — | US | disclosed |
| EP-2651890-B1 | STRIGOLACTAM DERIVATIVES AND THEIR USE AS PLANT GROWTH REGULATORS | SYNGENTA PARTICIPATIONS AG (CH) | 2014-09-10 | — | — | EP | disclosed |
| EP-2651890-B1 | STRIGOLACTAM DERIVATIVES AND THEIR USE AS PLANT GROWTH REGULATORS | SYNGENTA PARTICIPATIONS AG (CH) | 2014-09-10 | — | — | EP | disclosed |
| US-20130303375-A1 | PLANT GROWTH REGULATING COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2013-11-14 | — | — | US | disclosed |
| US-20130303375-A1 | PLANT GROWTH REGULATING COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2013-11-14 | — | — | US | disclosed |
| US-20130303375-A1 | PLANT GROWTH REGULATING COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2013-11-14 | — | — | US | disclosed |
| EP-2651890-A1 | STRIGOLACTAM DERIVATIVES AND THEIR USE AS PLANT GROWTH REGULATORS | Syngenta Participations AG (CH) | 2013-10-23 | — | — | EP | disclosed |
| WO-2012080115-A1 | STRIGOLACTAM DERIVATIVES AND THEIR USE AS PLANT GROWTH REGULATORS | SYNGENTA PARTICIPATIONS AG (CH) | 2012-06-21 | — | — | WO | disclosed |
| WO-2012080115-A1 | STRIGOLACTAM DERIVATIVES AND THEIR USE AS PLANT GROWTH REGULATORS | SYNGENTA PARTICIPATIONS AG (CH) | 2012-06-21 | — | — | WO | disclosed |
| EP-0991772-A1 | METHODS AND PRECURSORS FOR THE PRODUCTION OF CHIRAL VICINAL AMINOALCOHOLS | Biocatalytics, Inc. (US) | 2000-04-12 | — | — | EP | disclosed |
| US-5942644-A | Precursors for the production of chiral vicinal aminoalcohols | BIOCATALYTICS, INC. (US) | 1999-08-24 | — | — | US | disclosed |
| WO-1998054350-A1 | METHODS AND PRECURSORS FOR THE PRODUCTION OF CHIRAL VICINAL AMINOALCOHOLS | BIOCATALYTICS, INC. (US) | 1998-12-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130303375-A1 | PLANT GROWTH REGULATING COMPOUNDS | AREG, GHITM, FGF1 | ALDH1A1 3820/4885MAPT 3176/4885KDM4E 3805/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.