SCHEMBL8046954

SCHEMBL8046954

C=C(C)c1cccc(C(C)(C)OOC(C)(C)c2cccc(C(=C)C)c2C(C)(C)C)c1C(C)(C)C

nearest known ligand 0.35

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
CA2 P00918 1/20 0.35
GABRA1 P14867 1/20 0.32
GABRB2 P47870 1/20 0.32
MAPK1 P28482 1/20 0.31
TDP1 Q9NUW8 2/20 0.31
ALDH1A1 P00352 1/20 0.31
TSHR P16473 1/20 0.31
ATM Q13315 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31442923 0.77 MAPK1 (0.36) MAPK1TDP1ALDH1A1TSHRATM
SCHEMBL16702945 0.77 MAPK1 (0.36) MAPK1TDP1ALDH1A1TSHRATM
SCHEMBL16703772 0.77
SCHEMBL23413607 0.76 CA2 (0.32) CA2
SCHEMBL17825578 0.76 ALDH1A1 (0.30) TDP1ALDH1A1TSHR
SCHEMBL221698 0.75 CA2 (0.44) CA2GABRA1GABRB2MAPK1TDP1
SCHEMBL11432321 0.74 ALDH1A1 (0.39) CA2GABRA1GABRB2TDP1ALDH1A1
SCHEMBL24832884 0.73 CES2 (0.35) CA2ALDH1A1
SCHEMBL16703276 0.72
SCHEMBL2026303 0.71 GABRA1 (0.38) CA2GABRA1GABRB2MAPK1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3559153-B1 EFFICIENT CURATIVE FOR FREE RADICALLY-CROSSLINKABLE POLYMERS ARKEMA INC (US) 2025-07-30 EP disclosed
EP-3065944-B1 MODIFICATION OF POLYAMIDES ARKEMA INC (US) 2022-01-19 EP disclosed
US-11203672-B2 Efficient curative for free radically-crosslinkable polymers ARKEMA INC. (US) 2021-12-21 US disclosed
CN-110088233-B Effective curing agents for free-radical crosslinkable polymers 阿科玛股份有限公司 2021-09-21 CN disclosed
WO-2021104889-A1 FLAME-RETARDANT POLYMER COMPOSITION CARL FREUDENBERG KG (DE) 2021-06-03 WO disclosed
US-10787604-B2 Colored organic peroxide compositions and methods for breaking fluids ARKEMA INC. (US) 2020-09-29 US disclosed
CN-111465649-A Curable fluoroelastomers with low tendency to swell 科德宝两合公司 2020-07-28 CN disclosed
US-10569451-B1 Vulcanization of dip-molded rubber articles with reduced molten media bath times APEX MEDICAL TECHNOLOGIES, INC. (US) 2020-02-25 US disclosed
US-20190338086-A1 EFFICIENT CURATIVE FOR FREE RADICALLY-CROSSLINKABLE POLYMERS ARKEMA INC. 2019-11-07 US disclosed
EP-3559153-A1 EFFICIENT CURATIVE FOR FREE RADICALLY-CROSSLINKABLE POLYMERS Arkema, Inc. (US) 2019-10-30 EP disclosed
WO-2016043977-A1 COMPOSITIONS AND METHODS FOR BREAKING HYDRAULIC FRACTURING FLUIDS ARKEMA INC. (US) 2016-03-24 WO disclosed
US-20160009985-A1 PROMOTERS FOR PEROXIDES IN AQUEOUS TREATMENT FLUIDS ARKEMA INC. 2016-01-14 US disclosed
EP-2961923-A1 PROMOTERS FOR PEROXIDES IN AQUEOUS TREATMENT FLUIDS Arkema, Inc. (US) 2016-01-06 EP disclosed
US-9102866-B2 Radical trap in oil and gas stimulation operations ARKEMA INC. (US) 2015-08-11 US disclosed
WO-2015069455-A1 MODIFICATION OF POLYAMIDES ARKEMA INC. (US) 2015-05-14 WO disclosed
WO-2014133853-A1 PROMOTERS FOR PEROXIDES IN AQUEOUS TREATMENT FLUIDS ARKEMA INC. (US) 2014-09-04 WO disclosed
US-20120241158-A1 RADICAL TRAP IN OIL AND GAS STIMULATION OPERATIONS ARKEMA INC. (US) 2012-09-27 US disclosed
US-6107407-A COPOLYMERIZATION OF AN ALKYL (METH)ACRYLATE AND A PEROXYUNSATURATED COMPOUND; DISSOLVING OR SWELLING IN A MONOMER, E.G. STYRENE, FORMING THE HARD GRAFT SHELL; POLYMERIZATION OF THE MIXTURE INCLUDING A REDUCING AGENT BASF AKTIENGESELLSCHAFT (DE) 2000-08-22 US disclosed
EP-0579434-B1 Dialkyl peroxide, cross-linking composition containing the same, method for cross-linking, and electric power cable NOF CORP (JP) 1995-10-18 EP disclosed
EP-0579434-A1 Dialkyl peroxide, cross-linking composition containing the same, method for cross-linking, and electric power cable NOF CORPORATION (JP) 1994-01-19 EP disclosed