Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | DAO | P14920 | 1/20 | 0.40 |
| ▸ | ASPH | Q12797 | 1/20 | 0.40 |
| ▸ | RXRA | P19793 | 1/20 | 0.39 |
| ▸ | RXRB | P28702 | 1/20 | 0.39 |
| ▸ | CES2 | O00748 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CLCN2 | P51788 | 1/20 | 0.37 |
| ▸ | TAS2R14 | Q9NYV8 | 2/20 | 0.36 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.36 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | FABP4 | P15090 | 1/20 | 0.36 |
| ▸ | LDHA | P00338 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4849605 | 0.86 | DAO (0.44) | ALDH1A1HPGDDAOASPHRXRA | |
| SCHEMBL7565055 | 0.85 | ALDH1A1 (0.41) | ALDH1A1HPGDKDM4EHSD17B10DAO | |
| SCHEMBL4647359 | 0.84 | ALDH1A1 (0.43) | ALDH1A1HPGDKDM4EHSD17B10DAO | |
| SCHEMBL1099462 | 0.82 | ALDH1A1 (0.42) | ALDH1A1HPGDKDM4EHSD17B10DAO | |
| SCHEMBL22075506 | 0.81 | SELL (0.45) | ALDH1A1HPGDKDM4EHSD17B10DAO | |
| SCHEMBL19585173 | 0.81 | DAO (0.44) | ALDH1A1HPGDKDM4EHSD17B10DAO | |
| SCHEMBL10628408 | 0.81 | KDM4E (0.33) | ALDH1A1HPGDKDM4EHSD17B10DAO | |
| SCHEMBL23908710 | 0.79 | ALDH1A1 (0.47) | ALDH1A1HPGDTAS2R14GRIK1MEN1 | |
| SCHEMBL27990317 | 0.77 | ALDH1A1 (0.50) | ALDH1A1HPGDKDM4EHSD17B10DAO | |
| SCHEMBL1100670 | 0.76 | ASPH (0.42) | ALDH1A1HPGDKDM4EHSD17B10ASPH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6060615-A | Positively-chargeable charge control agent and toner for developing electrostatic images | ORIENT CHEMICAL INDUSTRIES, LTD. (JP) | 2000-05-09 | — | — | US | disclosed |
| US-5981130-A | Positively-chargeable charge control agent and toner for developing electrostatic images | ORIENT CHEMICAL INDUSTRIES, LTD. (JP) | 1999-11-09 | — | — | US | disclosed |
| EP-0881545-A1 | Positively-chargeable charge control agent and toner for developing electrostatic images | ORIENT CHEMICAL INDUSTRIES, LTD. (JP) | 1998-12-02 | — | — | EP | disclosed |
| US-4218464-A | 4- and 5-Substituted 2,3-dihydro-1H-isoindoles, pharmaceutical compositions and method of inhibiting phenylethanolamine N-methyltransferase | SMITHKLINE CORPORATION (US) | 1980-08-19 | — | — | US | disclosed |