SCHEMBL23908710

SCHEMBL23908710

O=C(O)c1ccc(-c2ccccc2C(F)(F)F)c(C(F)(F)F)c1C(=O)O

nearest known ligand 0.47

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.47
HPGD P15428 1/20 0.47
AKR1C3 P42330 2/20 0.43
AKR1C2 P52895 2/20 0.43
KMO O15229 2/20 0.43
TAS2R14 Q9NYV8 2/20 0.40
GRIK1 P39086 1/20 0.39
DHODH Q02127 2/20 0.39
MEN1 O00255 1/20 0.39
KMT2A Q03164 1/20 0.39
FABP4 P15090 1/20 0.39
LMNA P02545 2/20 0.38
GAA P10253 2/20 0.38
PTPN1 P18031 1/20 0.37
POLB P06746 1/20 0.37
FFAR4 Q5NUL3 1/20 0.37
EIF4E P06730 1/20 0.37
C1R P00736 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1099462 0.87 ALDH1A1 (0.42) ALDH1A1HPGDPOLB
SCHEMBL28636304 0.84 ALDH1A1 (0.51) ALDH1A1HPGDAKR1C3AKR1C2KMO
SCHEMBL11226095 0.83 ALDH1A1 (0.48) ALDH1A1HPGDAKR1C3AKR1C2KMO
SCHEMBL544646 0.83 ALDH1A1 (0.50) ALDH1A1HPGDAKR1C3AKR1C2KMO
SCHEMBL10626633 0.83 ALDH1A1 (0.40) ALDH1A1HPGDAKR1C3AKR1C2KMO
SCHEMBL4858140 0.81 ALDH1A1 (0.39) ALDH1A1HPGDAKR1C3AKR1C2KMO
SCHEMBL344491 0.79 ALDH1A1 (0.56) ALDH1A1HPGDAKR1C3AKR1C2KMO
SCHEMBL8047110 0.79 ALDH1A1 (0.41) ALDH1A1HPGDTAS2R14GRIK1MEN1
SCHEMBL11230568 0.77 ALDH1A1 (0.54) ALDH1A1HPGDAKR1C3AKR1C2KMO
SCHEMBL5851285 0.77 ALDH1A1 (0.54) ALDH1A1HPGDAKR1C3AKR1C2KMO

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3896114-B1 POLYIMIDE RESIN AND METHOD OF PRODUCING THE SAME, PHOTOSENSITIVE RESIN COMPOSITION, PATTERNING METHOD AND METHOD OF FORMING CURED FILM, INTERLAYER INSULATING FILM, SURFACE PROTECTIVE FILM, AND ELECTRONIC COMPONENT SHINETSU CHEMICAL CO (JP) 2023-10-18 EP disclosed
US-11572442-B2 Compound, polyimide resin and method of producing the same, photosensitive resin composition, patterning method and method of forming cured film, interlayer insulating film, surface protective film, and electronic component INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2023-02-07 US disclosed
EP-3896114-A1 NOVEL COMPOUND, POLYIMIDE RESIN AND METHOD OF PRODUCING THE SAME, PHOTOSENSITIVE RESIN COMPOSITION, PATTERNING METHOD AND METHOD OF FORMING CURED FILM, INTERLAYER INSULATING FILM, SURFACE PROTECTIVE FILM, AND ELECTRONIC COMPONENT Shin-Etsu Chemical Co., Ltd. (JP) 2021-10-20 EP disclosed
US-20210317270-A1 NOVEL COMPOUND, POLYIMIDE RESIN AND METHOD OF PRODUCING THE SAME, PHOTOSENSITIVE RESIN COMPOSITION, PATTERNING METHOD AND METHOD OF FORMING CURED FILM, INTERLAYER INSULATING FILM, SURFACE PROTECTIVE FILM, AND ELECTRONIC COMPONENT SHIN-ETSU CHEMICAL CO., LTD. (JP) 2021-10-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11572442-B2 Compound, polyimide resin and method of producing the same, photosensitive resin composition, patterning method and method of forming cured film, interlayer insulating film, surface protective film, and electronic component BRIX1, RBX1, HAX1 ALDH1A1 3045/4885HPGD 4207/4885AKR1C3 3444/4885
US-20210317270-A1 NOVEL COMPOUND, POLYIMIDE RESIN AND METHOD OF PRODUCING THE SAME, PHOTOSENSITIVE RESIN COMPOSITION, PATTERNING METHOD AND METHOD OF FORMING CURED FILM, INTERLAYER INSULATING FILM, SURFACE PROTECTIVE FILM, AND ELECTRONIC COMPONENT BRIX1, HAX1, RBX1 ALDH1A1 2917/4885HPGD 4114/4885AKR1C3 3251/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.