SCHEMBL1099462

SCHEMBL1099462

O=C(O)c1ccc(-c2ccc(C(=O)O)c(C(=O)O)c2C(F)(F)F)c(C(F)(F)F)c1C(=O)O

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.42
KDM4E B2RXH2 3/20 0.42
HPGD P15428 3/20 0.42
HSD17B10 Q99714 2/20 0.42
RXRA P19793 2/20 0.40
RXRB P28702 2/20 0.40
CYP1A2 P05177 1/20 0.39
CYP2C8 P10632 1/20 0.39
USP2 O75604 1/20 0.37
CYP2C19 P33261 1/20 0.37
ALOX15 P16050 1/20 0.34
NOTUM Q6P988 1/20 0.34
RXRG P48443 1/20 0.34
MPO P05164 1/20 0.34
MAPT P10636 2/20 0.33
ASPH Q12797 1/20 0.33
SELL P14151 1/20 0.33
SELP P16109 1/20 0.33
HDAC8 Q9BY41 1/20 0.33
DAO P14920 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23908710 0.87 ALDH1A1 (0.47) ALDH1A1HPGDPOLB
SCHEMBL4851323 0.85 RXRB (0.43) ALDH1A1KDM4EHPGDHSD17B10RXRA
SCHEMBL8047110 0.82 ALDH1A1 (0.41) ALDH1A1KDM4EHPGDHSD17B10RXRA
SCHEMBL7565055 0.82 ALDH1A1 (0.41) ALDH1A1KDM4EHPGDHSD17B10RXRA
SCHEMBL27990317 0.78 ALDH1A1 (0.50) ALDH1A1KDM4EHPGDHSD17B10RXRA
SCHEMBL434854 0.77 ALDH1A1 (0.41) ALDH1A1KDM4EHPGDHSD17B10RXRA
SCHEMBL1099692 0.76 ALDH1A1 (0.38) ALDH1A1KDM4EHPGDHSD17B10RXRA
SCHEMBL29962379 0.75 MEN1 (0.39) ALDH1A1KDM4EHPGDHSD17B10RXRA
SCHEMBL4858145 0.75 PTGDR2 (0.38) CYP2C8
SCHEMBL3755844 0.74 HTT (0.39) ALDH1A1KDM4EHPGDHSD17B10CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210139390-A1 PRODUCTION METHOD OF ORGANIC COMPOUND UNITIKA LTD. (JP) 2021-05-13 US disclosed
EP-3819283-A1 METHOD FOR PRODUCING ORGANIC COMPOUND Unitika Ltd. (JP) 2021-05-12 EP disclosed
WO-2021066011-A1 RESIN COMPOSITION, FILM, COMPOSITE MATERIAL, MOVABLE BODY, AND MATERIAL FOR THREE-DIMENSIONAL SHAPING USE 三菱ケミカル株式会社 2021-04-08 WO disclosed
CN-112469450-A Thermoplastic implant materials 沙特高性能聚合物和塑料全球技术公司 2021-03-09 CN disclosed
CN-105555535-A Fiber-reinforced polyaryletherketone resin composition SABIC GLOBAL TECHNOLOGIES BV 2016-05-04 CN disclosed
CN-105324435-A Wear resistant compositions with low particulate contamination and method of making those compositions SABIC INNOVATIVE PLASTICS IP 2016-02-10 CN disclosed
CN-105189646-A Improved wear and friction properties of engineering thermoplastics with ultra-high molecular weight polyethylene SABIC INNOVATIVE PLASTICS IP 2015-12-23 CN disclosed
CN-104641424-A Polymer nanocomposites for electronic applications SABIC INNOVATIVE PLASTICS LP 2015-05-20 CN disclosed
CN-103987766-A Coated polymer films SABIC INNOVATIVE PLASTICS IP 2014-08-13 CN disclosed
EP-2530103-A1 POLYIMIDE RESIN COMPOSITION, ADHESIVE AGENT AND LAMINATE EACH COMPRISING SAME, AND DEVICE Mitsui Chemicals, Inc. (JP) 2012-12-05 EP disclosed
US-6737503-B2 LOW TEMPERATURE ADHESIVE BONDING MITSUI CHEMICALS, INC. (JP) 2004-05-18 US disclosed
US-20040082754-A1 Novel aromatic diamine and polyimide thereof MITSUI CHEMICALS, INC. (JP) 2004-04-29 US disclosed
US-20030092870-A1 Novel aromatic diamine and polyimide thereof MITSUI CHEMICALS, INC. (JP) 2003-05-15 US disclosed
EP-1288191-A2 Novel aromatic diamine and polyimide thereof Mitsui Chemicals, Inc. (JP) 2003-03-05 EP disclosed
US-20010006767-A1 Developing solution and method of forming polyimide pattern by using the developing solution YOSHIAKI KAWAMONZEN 2001-07-05 US disclosed
US-6183934-B1 FOE USE IN FORMATION OF PATTERN OF INSULATION FILM, PASSIVATION FILM, .ALPHA.-RAY SHIELDING FILM, OPTICAL WAVEGUIDE KABUSHIKI KAISHA TOSHIBA (JP) 2001-02-06 US disclosed
US-6159654-A Negative photosensitive polymer composition of a thermosetting polymer precursor curable by cyclodehydration upon heating KABUSHIKI KAISHA TOSHIBA (JP) 2000-12-12 US disclosed
US-6001517-A A THERMOSETTING POLYMER WHICH CAN BE CURED THROUGH CYCLODEHYDRATION UPON HEATING AND A CURE ACCELERATOR WHICH CAN BE DEACTIVATED OF ITS CURE ACCELERATION PROPERTY BY IRRIDIATION OF LIGHT KABUSHIKI KAISHA TOSHIBA (JP) 1999-12-14 US disclosed
US-5756650-A COMPOSITION COMPRISING POLYAMIC ACID, CURE ACCELERATOR SELECTED FROM GROUP CONSISTING OF NITROGEN-CONTAINING HETEROCYCLIC COMPOUND, AMINO ACID COMPOUND, AROMATIC COMPOUND HAVING TWO OR MORE HYDROXYL GROUPS KABUSHIKI KAISHA TOSHIBA (JP) 1998-05-26 US disclosed
US-5578697-A DIELECTRIC POLYMERS FOR ELECTRONICS KABUSHIKI KAISHA TOSHIBA (JP) 1996-11-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030092870-A1 Novel aromatic diamine and polyimide thereof DDT, AOC1, H1-4 ALDH1A1 902/4885KDM4E 228/4885HPGD 3257/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.