Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 2/20 | 0.41 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | CFTR | P13569 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | DDR1 | Q08345 | 1/20 | 0.36 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.34 |
| ▸ | GSK3B | P49841 | 1/20 | 0.34 |
| ▸ | SORT1 | Q99523 | 4/20 | 0.33 |
| ▸ | MMP2 | P08253 | 1/20 | 0.33 |
| ▸ | MMP8 | P22894 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28813587 | 0.81 | LIPG (0.43) | CES2SLC6A9ALDH1A1KDM4EHPGD | |
| SCHEMBL28095379 | 0.80 | CES2 (0.49) | CES2SLC6A9ALDH1A1KDM4EHPGD | |
| SCHEMBL8490842 | 0.79 | CYP2C19 (0.42) | CES2SLC6A9ALDH1A1KDM4EHPGD | |
| SCHEMBL427104 | 0.79 | ALDH1A1 (0.57) | CES2SLC6A9ALDH1A1KDM4EHPGD | |
| SCHEMBL6751351 | 0.79 | CES2 (0.47) | CES2SLC6A9ALDH1A1KDM4EHPGD | |
| SCHEMBL29683463 | 0.79 | CES2 (0.47) | CES2SLC6A9ALDH1A1KDM4EHPGD | |
| SCHEMBL2325301 | 0.77 | KDM4E (0.47) | CES2SLC6A9ALDH1A1KDM4EHPGD | |
| SCHEMBL3028484 | 0.77 | CES2 (0.46) | CES2SLC6A9ALDH1A1KDM4EHPGD | |
| SCHEMBL6751338 | 0.76 | SLC6A9 (0.41) | CES2SLC6A9ALDH1A1KDM4EHPGD | |
| SCHEMBL29391001 | 0.76 | SLC6A9 (0.41) | CES2SLC6A9ALDH1A1KDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0994840-A1 | PROCESS FOR THE PREPARATION OF 1-ARYL-3-CYCLOPROPYL-1,3-PROPANEDIONES | Rhone Poulenc Agro (FR) | 2000-04-26 | — | — | EP | disclosed |
| WO-1999002476-A1 | PROCESS FOR THE PREPARATION OF 1-ARYL-3-CYCLOPROPYL-1,3-PROPANEDIONES | RHONE POULENC AGRO (FR) | 1999-01-21 | — | — | WO | disclosed |
| EP-0880498-A2 | PROCESS FOR PREPARING DIKETONE COMPOUNDS | RHONE-POULENC AGROCHIMIE (FR) | 1998-12-02 | — | — | EP | disclosed |
| WO-1997028122-A2 | PROCESS FOR PREPARING DIKETONE COMPOUNDS | RHONE-POULENC AGROCHIMIE (FR) | 1997-08-07 | — | — | WO | disclosed |