Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 5/20 | 0.42 |
| ▸ | MEN1 | O00255 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | NAAA | Q02083 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.41 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8047957 | 1.00 | KDM4E (0.48) | KDM4EPOLBMEN1KMT2ANAAA | |
| SCHEMBL11688085 | 0.87 | SMN1; SMN2 (0.50) | KDM4EMEN1KMT2ATSHRL3MBTL1 | |
| SCHEMBL8047962 | 0.80 | RAB9A (0.44) | KDM4EPOLBTDP1TSHRL3MBTL1 | |
| SCHEMBL8575690 | 0.78 | ALDH1A1 (0.43) | KDM4EL3MBTL1ALDH1A1SMN1; SMN2RAB9A | |
| SCHEMBL8058305 | 0.78 | ALDH1A1 (0.47) | KDM4ETDP1TSHRL3MBTL1ALDH1A1 | |
| SCHEMBL8575692 | 0.78 | ALDH1A1 (0.43) | KDM4EL3MBTL1ALDH1A1SMN1; SMN2RAB9A | |
| SCHEMBL8058307 | 0.78 | ALDH1A1 (0.47) | KDM4ETDP1TSHRL3MBTL1ALDH1A1 | |
| SCHEMBL21049314 | 0.76 | EPHX1 (0.42) | KDM4EPOLBMEN1KMT2ATDP1 | |
| SCHEMBL21049313 | 0.76 | EPHX1 (0.42) | KDM4EPOLBMEN1KMT2ATDP1 | |
| SCHEMBL8063735 | 0.76 | L3MBTL1 (0.46) | POLBTDP1TSHRL3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6162925-A | Antibiotic for methicillin resistant bacteria | RESEARCH CORPORATION TECH., INC. (US) | 2000-12-19 | — | — | US | disclosed |
| US-6110925-A | EFFECTIVE AGAINST STAPHYLOCOCCUS; ANTITUMOR AGENTS | RESEARCH CORPORATION TECHNOLOGIES, INC. (US) | 2000-08-29 | — | — | US | disclosed |
| EP-1003727-A1 | ANTIBIOTIC FOR METHICILLIN RESISTANT BACTERIA | RESEARCH CORPORATION TECHNOLOGIES (US) | 2000-05-31 | — | — | EP | disclosed |
| WO-1999007685-A1 | ANTIBIOTIC FOR METHICILLIN RESISTANT BACTERIA | RESEARCH CORPORATION TECHNOLOGIES, INC. (US) | 1999-02-18 | — | — | WO | disclosed |