SCHEMBL804800

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL14679813	0.88	TSHR (0.52)	TSHRKDM4EKLK7RAB9ARECQL
	SCHEMBL13943550	0.88	TSHR (0.52)	TSHRKDM4EKLK7RAB9ARECQL
	SCHEMBL804812	0.85	TSHR (0.68)	TSHRKDM4EKLK7RAB9AALDH1A1
	SCHEMBL12159623	0.85	TSHR (0.59)	TSHRKDM4EKLK7RAB9ARECQL
	SCHEMBL804994	0.83	TSHR (0.70)	TSHRKDM4EKLK7RAB9AALDH1A1
	SCHEMBL9002911	0.83	TSHR (0.60)	TSHRKDM4EKLK7RAB9ARECQL
	SCHEMBL804584	0.82	RECQL (0.64)	TSHRKDM4ERAB9ARECQLALDH1A1
	SCHEMBL13299515	0.82	TSHR (0.68)	TSHRKDM4EALDH1A1LMNAL3MBTL1
	SCHEMBL804809	0.80	TSHR (0.60)	TSHRKDM4EKLK7RAB9AALDH1A1
	SCHEMBL15605424	0.80	TSHR (1.00)	TSHRKDM4ERAB9AALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 172 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.