Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 4/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.56 |
| ▸ | MEN1 | O00255 | 5/20 | 0.56 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.56 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.56 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.56 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.56 |
| ▸ | EIF4H | Q15056 | 1/20 | 0.56 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 3/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | WDR5 | P61964 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 3/20 | 0.53 |
| ▸ | NPC1 | O15118 | 3/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8060211 | 0.87 | HTT (0.57) | HTTSMN1; SMN2KMT2AMEN1MAPT | |
| SCHEMBL8048033 | 0.85 | SMN1; SMN2 (0.58) | HTTSMN1; SMN2KMT2AMEN1PABPC1 | |
| SCHEMBL10224183 | 0.85 | RORC (0.57) | HTTSMN1; SMN2KMT2AMEN1PABPC1 | |
| SCHEMBL10224066 | 0.83 | KMT2A (0.56) | HTTSMN1; SMN2KMT2AMEN1PABPC1 | |
| SCHEMBL25394799 | 0.81 | KMT2A (0.56) | HTTSMN1; SMN2KMT2AMEN1PABPC1 | |
| SCHEMBL29074265 | 0.79 | KMT2A (0.64) | HTTKMT2AMEN1PABPC1DUSP3 | |
| SCHEMBL8057912 | 0.78 | KMT2A (0.64) | HTTSMN1; SMN2KMT2AMEN1MAPT | |
| SCHEMBL18147758 | 0.77 | MAPT (0.62) | HTTSMN1; SMN2KMT2AMEN1MAPT | |
| SCHEMBL18147762 | 0.77 | MAPT (0.62) | HTTSMN1; SMN2KMT2AMEN1MAPT | |
| SCHEMBL28581602 | 0.77 | WDR5 (0.62) | HTTSMN1; SMN2KMT2AMEN1PABPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009032749-A2 | SALICYLANILIDE MODIFIED PEPTIDES FOR USE AS ORAL THERAPEUTICS | THE REGENTS OF THE UNIVERSITY OF CALIFORNINA (US) | 2009-03-12 | — | — | WO | disclosed |
| WO-2008021088-A2 | SALICYLANILIDES ENHANCE ORAL DELIVERY OF THERAPEUTIC PEPTIDES | THE REGENTS OF THE UNIVERSITY OF CALIFORNINA (US) | 2008-02-21 | — | — | WO | disclosed |