Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 7/20 | 0.65 |
| ▸ | MMP1 | P03956 | 3/20 | 0.65 |
| ▸ | ADAMTS4 | O75173 | 2/20 | 0.65 |
| ▸ | MMP13 | P45452 | 2/20 | 0.65 |
| ▸ | MMP14 | P50281 | 2/20 | 0.65 |
| ▸ | ADAMTS5 | Q9UNA0 | 2/20 | 0.65 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.65 |
| ▸ | PGR | P06401 | 3/20 | 0.52 |
| ▸ | CA12 | O43570 | 5/20 | 0.52 |
| ▸ | CA1 | P00915 | 5/20 | 0.52 |
| ▸ | CA2 | P00918 | 5/20 | 0.52 |
| ▸ | CA9 | Q16790 | 5/20 | 0.52 |
| ▸ | CTSK | P43235 | 2/20 | 0.51 |
| ▸ | CTSS | P25774 | 1/20 | 0.51 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.50 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.50 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6557782 | 0.83 | MMP2 (0.64) | MMP2MMP1ADAMTS4MMP13MMP14 | |
| SCHEMBL7163404 | 0.82 | MMP2 (0.62) | MMP2MMP1ADAMTS4MMP13MMP14 | |
| SCHEMBL7247467 | 0.80 | MMP2 (0.72) | MMP2MMP1ADAMTS4MMP13MMP14 | |
| SCHEMBL5899447 | 0.79 | MMP2 (0.70) | MMP2MMP1ADAMTS4MMP13MMP14 | |
| SCHEMBL6557780 | 0.78 | MMP2 (0.61) | MMP2MMP1ADAMTS4MMP13MMP14 | |
| SCHEMBL7168984 | 0.78 | KAT6A (0.58) | MMP2MMP1ADAMTS4MMP13MMP14 | |
| SCHEMBL5954356 | 0.76 | FFAR1 (0.59) | PGRFFAR1FFAR4 | |
| SCHEMBL2838364 | 0.74 | MMP1 (0.64) | MMP2MMP1ADAMTS4MMP13MMP14 | |
| SCHEMBL7164010 | 0.73 | SGMS2 (0.53) | MMP2MMP1ADAMTS4MMP13MMP14 | |
| SCHEMBL5899507 | 0.73 | KAT6A (0.66) | MMP2MMP1ADAMTS4MMP13MMP14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6057362-A | Protease inhibitors | SMITHKLINE BEECHAM CORPORATION (US) | 2000-05-02 | — | — | US | disclosed |