Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.47 |
| ▸ | USP2 | O75604 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | RECQL | P46063 | 2/20 | 0.47 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8043621 | 0.89 | GLA (0.51) | MAPTMEN1KMT2AKDM4EGAA | |
| SCHEMBL8048634 | 0.84 | MAPT (0.47) | MAPTMEN1KMT2AKDM4EGAA | |
| SCHEMBL8044486 | 0.83 | SMN1; SMN2 (0.54) | MAPTMEN1KMT2AALDH1A1MAPK1 | |
| SCHEMBL8044799 | 0.83 | KMT2A (0.42) | MAPTMEN1KMT2AKDM4EGAA | |
| SCHEMBL8042947 | 0.82 | ALDH1A1 (0.46) | MAPTMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL8042618 | 0.82 | ALDH1A1 (0.50) | MAPTMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL8044615 | 0.81 | PDK1 (0.51) | MAPTMEN1KMT2AALDH1A1MAPK1 | |
| SCHEMBL8046503 | 0.80 | HSD17B10 (0.55) | MAPTMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL29647831 | 0.80 | MAPT (0.75) | MAPTMEN1KMT2AKDM4EGAA | |
| SCHEMBL3100413 | 0.80 | MAPT (0.75) | MAPTMEN1KMT2AKDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6080772-A | 2-AMINOTHIAZOLE TRIAZOLE OR TETRAZOLE COMPOUND FOR REGULATING PROTEIN TYROSINE PHOSPHATASE ACTIVITY | SUGEN, INC. (US) | 2000-06-27 | — | — | US | disclosed |