Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 13/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | DHODH | Q02127 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | FLT1 | P17948 | 1/20 | 0.42 |
| ▸ | KDR | P35968 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8060534 | 0.85 | HTT (0.52) | TRPV1MAPTNPC1NPSR1FLT1 | |
| SCHEMBL11375484 | 0.83 | IP6K1 (0.58) | MEN1KMT2ADHODHNPC1FLT1 | |
| SCHEMBL4332210 | 0.83 | CYP1A2 (0.47) | TRPV1MAPTMEN1KMT2ADHODH | |
| SCHEMBL15280716 | 0.83 | RAB9A (0.52) | MAPTMEN1KMT2ANPC1NPSR1 | |
| SCHEMBL10665627 | 0.82 | TRPV1 (0.55) | TRPV1MAPTMEN1KMT2A | |
| SCHEMBL14840387 | 0.81 | IP6K1 (0.47) | MAPTMEN1KMT2ANPC1FLT1 | |
| SCHEMBL22467553 | 0.81 | ALDH1A1 (0.46) | MAPTMEN1KMT2ADHODHNPC1 | |
| SCHEMBL13508 | 0.81 | PTGS1 (0.51) | MAPTMEN1KMT2ADHODH | |
| SCHEMBL14789796 | 0.81 | RAB9A (0.51) | MAPTMEN1KMT2ANPC1NPSR1 | |
| SCHEMBL928538 | 0.81 | PTGS1 (0.54) | MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1265643-A | Anthranilic acid analogs | AMERICAN HOME PROD (US) | 2000-09-06 | — | — | CN | disclosed |
| US-6096770-A | ADMINISTERING ORALLY OR PARENTALLY, TO A PATIENT AN ANTHRANILIC ACID DERIVATIVE FOR REDUCING THE ADVERSE EFFECTS OF SMOOTH MUSCLE CONTRACTIONS | AMERICAN HOME PRODUCTS CORPORATION (US) | 2000-08-01 | — | — | US | disclosed |
| EP-1003713-A1 | ANTHRANILIC ACID ANALOGS | AMERICAN HOME PRODUCTS CORPORATION (US) | 2000-05-31 | — | — | EP | disclosed |
| WO-1999007670-A1 | ANTHRANILIC ACID ANALOGS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1999-02-18 | — | — | WO | disclosed |