Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB1 | P05556 | 1/20 | 0.48 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.48 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.48 |
| ▸ | CACNA1B | Q00975 | 4/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2058594 | 1.00 | ITGB1 (0.48) | ITGB1ITGA4ITGB7CACNA1BRAB9A | |
| SCHEMBL4618111 | 0.91 | SMN1; SMN2 (0.52) | ITGB1ITGA4ITGB7CACNA1BRAB9A | |
| SCHEMBL13043085 | 0.88 | RAB9A (0.39) | ITGB1ITGA4ITGB7CACNA1BRAB9A | |
| SCHEMBL2058808 | 0.85 | ITGB1 (0.48) | ITGB1ITGA4ITGB7RAB9AMAPT | |
| SCHEMBL2857963 | 0.84 | ITGB1 (0.57) | ITGB1ITGA4ITGB7MAPTALDH1A1 | |
| SCHEMBL8060168 | 0.84 | ITGB1 (0.57) | ITGB1ITGA4ITGB7MAPTALDH1A1 | |
| SCHEMBL2059100 | 0.78 | P2RX7 (0.59) | ITGB1ITGA4ITGB7CACNA1B | |
| SCHEMBL10535089 | 0.78 | MAPT (0.55) | MAPTSMN1; SMN2HTTALDH1A1POLB | |
| SCHEMBL17822347 | 0.77 | ALDH1A1 (0.55) | ITGB1ITGA4ITGB7RAB9AMAPT | |
| SCHEMBL17822346 | 0.77 | ALDH1A1 (0.55) | ITGB1ITGA4ITGB7RAB9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1000051-A1 | CARBAMYLOXY COMPOUNDS WHICH INHIBIT LEUKOCYTE ADHESION MEDIATED BY VLA-4 | Elan Pharmaceuticals, Inc. (US) | 2000-05-17 | — | — | EP | claimed |
| WO-1999006390-A1 | CARBAMYLOXY COMPOUNDS WHICH INHIBIT LEUKOCYTE ADHESION MEDIATED BY VLA-4 | ELAN PHARMACEUTICALS, INC. (US) | 1999-02-11 | — | — | WO | claimed |