Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | LTA4H | P09960 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.41 |
| ▸ | HTR2B | P41595 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.40 |
| ▸ | FAAH | O00519 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8034448 | 1.00 | TSHR (0.45) | TSHRLMNAALDH1A1LTA4HCYP3A4 | |
| SCHEMBL2473998 | 0.93 | LTA4H (0.44) | TSHRLMNAALDH1A1LTA4HCYP3A4 | |
| SCHEMBL8052071 | 0.91 | SOAT2 (0.45) | ALDH1A1SOAT1FAAH | |
| SCHEMBL8052068 | 0.91 | SOAT2 (0.45) | ALDH1A1SOAT1FAAH | |
| SCHEMBL1686754 | 0.86 | TSHR (0.45) | TSHRLMNAALDH1A1LTA4HCYP3A4 | |
| SCHEMBL1686488 | 0.86 | TSHR (0.45) | TSHRLMNAALDH1A1LTA4HCYP3A4 | |
| SCHEMBL1686749 | 0.86 | TSHR (0.45) | TSHRLMNAALDH1A1LTA4HCYP3A4 | |
| SCHEMBL1687034 | 0.86 | TSHR (0.45) | TSHRLMNAALDH1A1LTA4HCYP3A4 | |
| SCHEMBL1686936 | 0.86 | TSHR (0.45) | TSHRLMNAALDH1A1LTA4HCYP3A4 | |
| SCHEMBL1686459 | 0.84 | LTA4H (0.44) | TSHRLMNAALDH1A1LTA4HCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0558449-B1 | Complexes of chelating ligands and process for their preparation | NOVARTIS AG (CH) | 2000-09-06 | — | — | EP | disclosed |
| US-5686439-A | Chelate complexes and processes for their preparation | NOVARTIS CORPORATION (US) | 1997-11-11 | — | — | US | disclosed |
| US-5670491-A | Chelate complexes and processes for their preparation | CIBA-GEIGY CORPORATION (US) | 1997-09-23 | — | — | US | disclosed |
| US-5358940-A | Chelate complexes and processes for their preparation | CIBA-GEIGY CORPORATION (US) | 1994-10-25 | — | — | US | disclosed |
| EP-0558449-A1 | Complexes of chelating ligands and process for their preparation | CIBA-GEIGY AG (CH) | 1993-09-01 | — | — | EP | disclosed |