Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOAT2 | O75908 | 1/20 | 0.45 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.45 |
| ▸ | FAAH | O00519 | 5/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.43 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.42 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.42 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.42 |
| ▸ | CES1 | P23141 | 2/20 | 0.41 |
| ▸ | CNR1 | P21554 | 2/20 | 0.41 |
| ▸ | CNR2 | P34972 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8052068 | 1.00 | SOAT2 (0.45) | SOAT2SOAT1FAAHEPHX2LPAR1 | |
| SCHEMBL8048262 | 0.91 | TSHR (0.45) | SOAT1FAAHALDH1A1 | |
| SCHEMBL8034448 | 0.91 | TSHR (0.45) | SOAT1FAAHALDH1A1 | |
| SCHEMBL2473998 | 0.84 | LTA4H (0.44) | ALDH1A1 | |
| SCHEMBL1686936 | 0.81 | TSHR (0.45) | SOAT1FAAHALDH1A1 | |
| SCHEMBL1686488 | 0.81 | TSHR (0.45) | SOAT1FAAHALDH1A1 | |
| SCHEMBL1686749 | 0.81 | TSHR (0.45) | SOAT1FAAHALDH1A1 | |
| SCHEMBL1687034 | 0.81 | TSHR (0.45) | SOAT1FAAHALDH1A1 | |
| SCHEMBL1686754 | 0.81 | TSHR (0.45) | SOAT1FAAHALDH1A1 | |
| SCHEMBL4341940 | 0.80 | PPARG (0.41) | SOAT2SOAT1FAAHEPHX2LPAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0558449-B1 | Complexes of chelating ligands and process for their preparation | NOVARTIS AG (CH) | 2000-09-06 | — | — | EP | disclosed |
| US-5686439-A | Chelate complexes and processes for their preparation | NOVARTIS CORPORATION (US) | 1997-11-11 | — | — | US | disclosed |
| US-5670491-A | Chelate complexes and processes for their preparation | CIBA-GEIGY CORPORATION (US) | 1997-09-23 | — | — | US | disclosed |
| US-5358940-A | Chelate complexes and processes for their preparation | CIBA-GEIGY CORPORATION (US) | 1994-10-25 | — | — | US | disclosed |
| EP-0558449-A1 | Complexes of chelating ligands and process for their preparation | CIBA-GEIGY AG (CH) | 1993-09-01 | — | — | EP | disclosed |