Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.33 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 3/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.32 |
| ▸ | RXRA | P19793 | 1/20 | 0.32 |
| ▸ | RXRB | P28702 | 1/20 | 0.32 |
| ▸ | RXRG | P48443 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8047063 | 0.80 | TSHR (0.51) | MAPTALDH1A1MEN1KMT2ATSHR | |
| SCHEMBL8042116 | 0.80 | SMN1; SMN2 (0.41) | MAPTALDH1A1MEN1KMT2ATSHR | |
| SCHEMBL8044772 | 0.80 | MAPT (0.38) | MAPTALDH1A1MEN1KMT2ANPSR1 | |
| SCHEMBL8042649 | 0.79 | ALDH1A1 (0.36) | MAPTALDH1A1MEN1KMT2ATSHR | |
| SCHEMBL8044969 | 0.79 | ALDH1A1 (0.45) | MAPTALDH1A1HDAC6HPGDNPSR1 | |
| SCHEMBL8048718 | 0.79 | RPA1 (0.50) | MAPTALDH1A1MEN1KMT2ATSHR | |
| SCHEMBL8043019 | 0.78 | HDAC6 (0.38) | MAPTALDH1A1MEN1KMT2ATSHR | |
| SCHEMBL8044342 | 0.78 | ALPG (0.43) | MAPTALDH1A1MEN1KMT2ATSHR | |
| SCHEMBL8044735 | 0.78 | SMN1; SMN2 (0.40) | MAPTHDAC6NPSR1HTTSMN1; SMN2 | |
| SCHEMBL8050060 | 0.77 | HTT (0.46) | MAPTALDH1A1MEN1KMT2ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6080772-A | 2-AMINOTHIAZOLE TRIAZOLE OR TETRAZOLE COMPOUND FOR REGULATING PROTEIN TYROSINE PHOSPHATASE ACTIVITY | SUGEN, INC. (US) | 2000-06-27 | — | — | US | disclosed |