Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 1/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 6/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | RARB | P10826 | 2/20 | 0.35 |
| ▸ | RARG | P13631 | 1/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 4/20 | 0.35 |
| ▸ | GABRG2 | P18507 | 4/20 | 0.35 |
| ▸ | GABRB3 | P28472 | 4/20 | 0.35 |
| ▸ | GABRA5 | P31644 | 4/20 | 0.35 |
| ▸ | GABRA3 | P34903 | 4/20 | 0.35 |
| ▸ | GABRA2 | P47869 | 4/20 | 0.35 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP3A5 | P20815 | 1/20 | 0.34 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.32 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.31 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.31 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27134342 | 0.93 | CYP19A1 (0.49) | SLC2A1CYP19A1RARBRARGGABRA1 | |
| SCHEMBL27133977 | 0.88 | APP (0.47) | CYP19A1CYP3A4 | |
| SCHEMBL27134521 | 0.88 | ACACB (0.36) | SLC2A1CYP19A1GABRA1GABRG2GABRB3 | |
| SCHEMBL27134431 | 0.85 | MAPT (0.43) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL437002 | 0.83 | RARB (0.37) | RARBRARGGABRA1GABRG2GABRB3 | |
| SCHEMBL1306384 | 0.82 | GABRA1 (0.38) | RAB9AGABRA1GABRG2GABRB3GABRA5 | |
| SCHEMBL8960251 | 0.81 | RARB (0.48) | RAB9ARARBRARGGABRA1GABRG2 | |
| SCHEMBL1306505 | 0.79 | APP (0.41) | RAB9AGABRA1GABRG2GABRB3GABRA5 | |
| SCHEMBL3348211 | 0.79 | KIF11 (0.44) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL27139570 | 0.78 | CYP19A1 (0.39) | CYP19A1GABRA1GABRG2GABRB3GABRA5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6140503-A | Organometallic compounds | ACADEMIA SINICA (TW) | 2000-10-31 | — | — | US | disclosed |