Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 3/20 | 0.50 |
| ▸ | CES2 | O00748 | 2/20 | 0.42 |
| ▸ | CES1 | P23141 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 5/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | HTT | P42858 | 3/20 | 0.42 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.39 |
| ▸ | PKM | P14618 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | ATM | Q13315 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.39 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4599993 | 0.82 | CYP19A1 (0.48) | PTGS2CES2CES1ESR1ALDH1A1 | |
| SCHEMBL1075458 | 0.79 | ESR1 (0.44) | LMNAMAPTESR1ALDH1A1SMN1; SMN2 | |
| SCHEMBL2509405 | 0.77 | PTGS2 (0.42) | PTGS2CES2CES1LMNAMAPT | |
| SCHEMBL6304315 | 0.76 | ESR1 (0.41) | PTGS2MAPTESR1ALDH1A1SMN1; SMN2 | |
| SCHEMBL6304314 | 0.76 | ESR1 (0.41) | PTGS2MAPTESR1ALDH1A1SMN1; SMN2 | |
| SCHEMBL29222532 | 0.75 | PTGS2 (0.68) | PTGS2CES2CES1MAPTESR1 | |
| SCHEMBL9026538 | 0.75 | PTGS2 (0.73) | PTGS2CES2CES1MAPTESR1 | |
| SCHEMBL9026535 | 0.75 | PTGS2 (0.73) | PTGS2CES2CES1MAPTESR1 | |
| SCHEMBL13992020 | 0.75 | ALDH1A1 (0.41) | PTGS2MAPTESR1ALDH1A1MEN1 | |
| SCHEMBL6297971 | 0.74 | PTGS2 (0.40) | PTGS2ESR1ALDH1A1SMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6093864-A | Aromatic dimethylidyne compounds | IDEMITSU KOSAN CO., LTD. (JP) | 2000-07-25 | — | — | US | disclosed |
| EP-0388768-B1 | Organic electroluminescent device containing aromatic dimethylidyne compounds | IDEMITSU KOSAN CO (JP) | 1995-08-09 | — | — | EP | disclosed |
| EP-0616020-A1 | Aromatic dimethylidyne compounds and process for preparation thereof | IDEMITSU KOSAN COMPANY LIMITED (JP) | 1994-09-21 | — | — | EP | disclosed |
| US-5130603-A | A stilbene, bluish purple to green | IDEMITSU KOSAN CO., LTD. (JP) | 1992-07-14 | — | — | US | disclosed |
| EP-0388768-A2 | Organic electroluminescent device containing aromatic dimethylidyne compounds | IDEMITSU KOSAN COMPANY LIMITED (JP) | 1990-09-26 | — | — | EP | disclosed |