SCHEMBL1075458

SCHEMBL1075458

C(=C(c1ccc(-c2ccccc2)cc1)c1ccc(-c2ccccc2)cc1)c1c2ccccc2c(C=C(c2ccc(-c3ccccc3)cc2)c2ccc(-c3ccccc3)cc2)c2ccccc12

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 1/20 0.44
SMN1; SMN2 Q16637 4/20 0.42
MAPT P10636 2/20 0.42
WDR5 P61964 1/20 0.42
L3MBTL1 Q9Y468 2/20 0.40
HPGD P15428 1/20 0.40
RAB9A P51151 2/20 0.39
NPC1 O15118 1/20 0.39
CTDSP1 Q9GZU7 1/20 0.39
MMP3 P08254 1/20 0.39
BCL2L1 Q07817 1/20 0.39
PTPN1 P18031 1/20 0.38
GSK3B P49841 1/20 0.38
TP53 P04637 1/20 0.38
CYP19A1 P11511 1/20 0.38
CYP11B2 P19099 1/20 0.38
MEN1 O00255 1/20 0.38
POLB P06746 1/20 0.38
KMT2A Q03164 1/20 0.38
ALDH1A1 P00352 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4599993 0.87 CYP19A1 (0.48) ESR1L3MBTL1CYP19A1CYP11B2ALDH1A1
SCHEMBL6304315 0.80 ESR1 (0.41) ESR1SMN1; SMN2MAPTHPGDRAB9A
SCHEMBL6304314 0.80 ESR1 (0.41) ESR1SMN1; SMN2MAPTHPGDRAB9A
SCHEMBL8050557 0.79 PTGS2 (0.50) ESR1SMN1; SMN2MAPTHPGDRAB9A
SCHEMBL13992020 0.79 ALDH1A1 (0.41) ESR1MAPTL3MBTL1HPGDRAB9A
SCHEMBL10896979 0.77 ESR1 (0.67) ESR1MAPTHPGDRAB9ANPC1
SCHEMBL13656651 0.76 HSD17B1 (0.45) RAB9AMEN1POLBKMT2A
SCHEMBL2499605 0.76 RAB9A (0.38) ESR1SMN1; SMN2MAPTWDR5L3MBTL1
SCHEMBL2499606 0.76 RAB9A (0.38) ESR1SMN1; SMN2MAPTWDR5L3MBTL1
Triphenylene SCHEMBL28978119 0.75 CYP19A1 (0.57) ESR1MAPTHPGDTP53CYP19A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1063869-B1 METHOD FOR SELECTING ORGANIC COMPOUNDS FOR ORGANIC ELECTROLUMINESCENT DEVICE IDEMITSU KOSAN CO (JP) 2011-04-06 EP disclosed
EP-2270117-A2 Organic electroluminescence device Idemitsu Kosan Co., Ltd. (JP) 2011-01-05 EP disclosed
US-20060159959-A1 Organic electroluminescence device with organic compound layer containing lower than 500 ppm of a halogen-containing compound IDEMITSU KOSAN CO., LTD. (JP) 2006-07-20 US disclosed
US-7045950-B2 Organic electroluminescence device with organic compound layer containing lower than 500 PPM of a halogen-containing compound IDEMITSU KOSAN CO., LTD. (JP) 2006-05-16 US disclosed
US-6617051-B1 Organic emitting layer sandwiched between a pair of electrodes, wherein at least one organic compound layer is formed from an organic compound material having an impurity concentration of lower than 1000 ppm. IDEMITSU KOSAN CO., LTD. (JP) 2003-09-09 US disclosed
EP-1063869-A1 ORGANIC ELECTROLUMINESCENCE DEVICE IDEMITSU KOSAN COMPANY LIMITED (JP) 2000-12-27 EP disclosed