Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 8/20 | 0.58 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.58 |
| ▸ | ADRA2A | P08913 | 3/20 | 0.58 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.58 |
| ▸ | DRD1 | P21728 | 3/20 | 0.58 |
| ▸ | DRD3 | P35462 | 3/20 | 0.58 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.58 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.58 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.58 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.58 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.58 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.58 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.58 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.58 |
| ▸ | HTR2A | P28223 | 1/20 | 0.58 |
| ▸ | HTR2C | P28335 | 1/20 | 0.58 |
| ▸ | HRH1 | P35367 | 1/20 | 0.58 |
| ▸ | HTR2B | P41595 | 1/20 | 0.58 |
| ▸ | MC4R | P32245 | 5/20 | 0.56 |
| ▸ | OPRD1 | P41143 | 6/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL31635746 | 0.88 | OPRM1 (0.69) | OPRM1CHRM2ADRA2ACHRM1DRD1 | |
| SCHEMBL9258176 | 0.79 | OPRM1 (0.54) | OPRM1CHRM2ADRA2ACHRM1DRD1 | |
| SCHEMBL8963664 | 0.79 | MEN1 (0.56) | OPRM1CYP2D6OPRD1OPRK1OPRL1 | |
| SCHEMBL12875000 | 0.78 | MC4R (0.65) | OPRM1CHRM2ADRA2ACHRM1DRD1 | |
| SCHEMBL13984355 | 0.76 | MC4R (0.49) | OPRM1CHRM2ADRA2ACHRM1DRD1 | |
| Hydrochloric Acid SCHEMBL3639303 | 0.75 | MC4R (0.48) | OPRM1CHRM2ADRA2ACHRM1DRD1 | |
| SCHEMBL9247567 | 0.74 | OPRM1 (0.49) | OPRM1ADRA2ASLC6A3MC4ROPRD1 | |
| Cyclizine SCHEMBL4690 | 0.74 | CYP2D6 (1.00) | OPRM1CHRM2ADRA2ACHRM1DRD1 | |
| SCHEMBL7927379 | 0.73 | CHRM2 (0.49) | OPRM1CHRM2ADRA2ACHRM1DRD1 | |
| Cyclizine SCHEMBL97825 | 0.72 | CYP2D6 (0.96) | OPRM1CHRM2ADRA2ACHRM1DRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0995741-A1 | REMEDIES/PREVENTIVES FOR FREQUENT URINATION/URINARY INCONTINENCE AND TROPONE DERIVATIVES | Nippon Kayaku Kabushiki Kaisha (JP) | 2000-04-26 | — | — | EP | disclosed |