Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VDR | P11473 | 11/20 | 0.73 |
| ▸ | HDAC6 | Q9UBN7 | 7/20 | 0.68 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.68 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.67 |
| ▸ | CYP24A1 | Q07973 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19560766 | 0.92 | VDR (0.63) | VDRHDAC6HDAC3HDAC2 | |
| SCHEMBL26756333 | 0.90 | VDR (0.63) | VDR | |
| SCHEMBL1248608 | 0.90 | VDR (0.70) | VDRHDAC6HDAC3HDAC2CYP24A1 | |
| SCHEMBL1248611 | 0.90 | VDR (0.70) | VDRHDAC6HDAC3HDAC2CYP24A1 | |
| SCHEMBL14544644 | 0.90 | VDR (0.70) | VDRHDAC6HDAC3HDAC2CYP24A1 | |
| SCHEMBL14643170 | 0.89 | VDR (0.80) | VDRHDAC6HDAC3HDAC2 | |
| SCHEMBL798360 | 0.89 | VDR (0.59) | VDRHDAC6HDAC3 | |
| SCHEMBL9009931 | 0.89 | VDR (0.59) | VDRHDAC6HDAC3 | |
| Becocalcidiol SCHEMBL23752369 | 0.88 | VDR (0.76) | VDRCYP24A1 | |
| Becocalcidiol SCHEMBL9009928 | 0.88 | VDR (0.76) | VDRCYP24A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120071562-A1 | 2alpha-Methyl-19-Nor-(20S)-1alpha-Hydroxy-Bishomopregnacalciferol and Its Uses | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2012-03-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120071562-A1 | 2alpha-Methyl-19-Nor-(20S)-1alpha-Hydroxy-Bishomopregnacalciferol and Its Uses | CYP24A1, CYP27B1, CYP2R1 | VDR 4/4885HDAC6 4810/4885HDAC3 4092/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.