Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VDR | P11473 | 6/20 | 0.59 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.55 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9009931 | 1.00 | VDR (0.59) | VDRHDAC3HDAC6 | |
| SCHEMBL19560766 | 0.90 | VDR (0.63) | VDRHDAC3HDAC6 | |
| SCHEMBL14357527 | 0.90 | VDR (0.66) | VDRHDAC3HDAC6 | |
| SCHEMBL14357530 | 0.90 | VDR (0.66) | VDRHDAC3HDAC6 | |
| SCHEMBL9009932 | 0.90 | VDR (0.66) | VDRHDAC3HDAC6 | |
| SCHEMBL805084 | 0.89 | VDR (0.73) | VDRHDAC3HDAC6 | |
| SCHEMBL12190406 | 0.89 | VDR (0.65) | VDRHDAC3HDAC6 | |
| SCHEMBL12190410 | 0.89 | VDR (0.65) | VDRHDAC3HDAC6 | |
| SCHEMBL22422512 | 0.89 | VDR (0.65) | VDRHDAC3HDAC6 | |
| SCHEMBL9009944 | 0.89 | VDR (0.55) | VDRHDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8188064-B2 | Reducing cell differentiation of adipocyte; reducing body fat | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2012-05-29 | — | — | US | disclosed |
| US-8188064-B2 | Reducing cell differentiation of adipocyte; reducing body fat | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2012-05-29 | — | — | US | disclosed |
| US-20120071562-A1 | 2alpha-Methyl-19-Nor-(20S)-1alpha-Hydroxy-Bishomopregnacalciferol and Its Uses | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2012-03-22 | — | — | US | disclosed |
| US-20120071562-A1 | 2alpha-Methyl-19-Nor-(20S)-1alpha-Hydroxy-Bishomopregnacalciferol and Its Uses | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2012-03-22 | — | — | US | disclosed |
| US-8093232-B2 | 2α-methyl-19-nor-(20S)-1α-hydroxy-bishomopregnacalciferol and its uses | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2012-01-10 | — | — | US | disclosed |
| US-8093232-B2 | 2α-methyl-19-nor-(20S)-1α-hydroxy-bishomopregnacalciferol and its uses | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2012-01-10 | — | — | US | disclosed |
| US-20070254857-A1 | 2Alpha-Methyl-19-Nor-(20S)-1Alpha-Hydroxy-Bishomopregnacalciferol and Its Uses | WISCONSIN ALUMNI RESEARCH FOUNDATION, A NON-STOCK, NON-PROFIT WISCONSIN CORPORATION (US) | 2007-11-01 | — | — | US | disclosed |
| US-20070254857-A1 | 2Alpha-Methyl-19-Nor-(20S)-1Alpha-Hydroxy-Bishomopregnacalciferol and Its Uses | WISCONSIN ALUMNI RESEARCH FOUNDATION, A NON-STOCK, NON-PROFIT WISCONSIN CORPORATION (US) | 2007-11-01 | — | — | US | disclosed |
| US-7241751-B2 | 2α-methyl-19-nor-(20S)-1α-hydroxy-bishomopregnacalciferol and its uses | WISCONSIN ALUMI RESEARCH FOUNDATION (US) | 2007-07-10 | — | — | US | disclosed |
| US-7241751-B2 | 2α-methyl-19-nor-(20S)-1α-hydroxy-bishomopregnacalciferol and its uses | WISCONSIN ALUMI RESEARCH FOUNDATION (US) | 2007-07-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120071562-A1 | 2alpha-Methyl-19-Nor-(20S)-1alpha-Hydroxy-Bishomopregnacalciferol and Its Uses | CYP24A1, CYP27B1, CYP2R1 | VDR 4/4885HDAC3 4092/4885HDAC6 4810/4885 |
| US-20070254857-A1 | 2Alpha-Methyl-19-Nor-(20S)-1Alpha-Hydroxy-Bishomopregnacalciferol and Its Uses | CYP24A1, CYP27B1, CYP2R1 | VDR 4/4885HDAC3 4092/4885HDAC6 4810/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.