Urea

Urea

SCHEMBL8051050

CCC(CO)CO.NC(N)=O

nearest known ligand 0.46

Full drug profile on Sugi Atlas →

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.46
CA2 P00918 3/20 0.36
CA1 P00915 1/20 0.36
LMNA P02545 5/20 0.35
TDP1 Q9NUW8 2/20 0.35
OR51E2 Q9H255 1/20 0.35
TRPA1 O75762 1/20 0.34
ALOX15 P16050 2/20 0.33
BLM P54132 1/20 0.32
PMP22 Q01453 1/20 0.32
SLC1A3 P43003 1/20 0.31
SLC1A2 P43004 1/20 0.31
SLC1A1 P43005 1/20 0.31
KDM4E B2RXH2 2/20 0.31
CNR1 P21554 1/20 0.31
ADRA1A P35348 1/20 0.31
LAP3 P28838 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Bicarbonate SCHEMBL4650917 0.85 ALDH1A1 (0.48) ALDH1A1CA2LMNATDP1OR51E2
SCHEMBL50253 0.84
Acetic Acid SCHEMBL5373299 0.82 ALDH1A1 (0.46) ALDH1A1CA2LMNATDP1OR51E2
Acetic Acid SCHEMBL6419060 0.82 ALDH1A1 (0.46) ALDH1A1CA2LMNATDP1OR51E2
SCHEMBL5955330 0.81
Ammonia Solution, Strong SCHEMBL11672040 0.81
SCHEMBL3684682 0.78 ALDH1A1 (0.48) ALDH1A1CA2CA1LMNATDP1
SCHEMBL22160 0.77
SCHEMBL22286874 0.76 ALOX15 (0.46) ALDH1A1CA2LMNATDP1ALOX15
Benzene SCHEMBL11077172 0.75 TRPA1 (0.52) ALDH1A1LMNATDP1TRPA1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6074964-A FABRIC WITH CELLULOSE FIBERS AND ACRYLAMIDO-2-METHYLPROPANE SULFONIC ACID AND SODIUM ALLYLSULFONATE GRAFT POLYMER TORAY INDUSTRIES, INC. (JP) 2000-06-13 US disclosed
EP-0814191-A1 FIBER STRUCTURES AND PROCESS FOR THE PRODUCTION THEREOF TORAY INDUSTRIES, INC. (JP) 1997-12-29 EP disclosed
EP-0811718-A1 WOVEN OR KNITTED GOODS AND PROCESS FOR PRODUCTION THEREOF TORAY INDUSTRIES, INC. (JP) 1997-12-10 EP disclosed