Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | ELANE | P08246 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | CDK8 | P49336 | 2/20 | 0.33 |
| ▸ | CDK19 | Q9BWU1 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | PRKCI | P41743 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.31 |
| ▸ | IKBKB | O14920 | 4/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5987101 | 0.98 | GAA (0.47) | GAAALDH1A1HSD17B10HPGDALOX15 | |
| SCHEMBL6653068 | 0.71 | ALDH1A1 (0.32) | GAAALDH1A1HPGDALOX15MAPT | |
| SCHEMBL7474075 | 0.70 | GAA (0.52) | GAAALDH1A1HSD17B10HPGDALOX15 | |
| Hydrochloric Acid SCHEMBL6652810 | 0.69 | ALDH1A1 (0.31) | GAAALDH1A1HPGDALOX15MAPT | |
| SCHEMBL5988926 | 0.65 | GAA (1.00) | GAAALDH1A1HSD17B10HPGDALOX15 | |
| SCHEMBL21548186 | 0.64 | ALDH1A1 (0.47) | GAAALDH1A1HSD17B10HPGDALOX15 | |
| SCHEMBL20212134 | 0.64 | GAA (0.45) | GAAALDH1A1HSD17B10HPGDALOX15 | |
| SCHEMBL16172596 | 0.64 | GPR35 (0.46) | GAAALDH1A1HSD17B10HPGDALOX15 | |
| SCHEMBL27224479 | 0.64 | GAA (0.46) | GAAALDH1A1HSD17B10HPGDALOX15 | |
| SCHEMBL30216470 | 0.62 | ALDH1A1 (0.66) | GAAALDH1A1HSD17B10HPGDALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6114358-A | Thrombin inhibitors | BASF AKTIENGESELLSCHAFT (DE) | 2000-09-05 | — | — | US | disclosed |