Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6652810 | 0.98 | ALDH1A1 (0.31) | ALDH1A1GAAMAPTHPGDSMN1; SMN2 | |
| SCHEMBL8052245 | 0.71 | GAA (0.48) | ALDH1A1GAAMAPTHPGDALOX15 | |
| SCHEMBL7471882 | 0.70 | GAA (0.33) | ALDH1A1GAAHPGD | |
| Hydrochloric Acid SCHEMBL5987101 | 0.69 | GAA (0.47) | ALDH1A1GAAMAPTHPGDALOX15 | |
| SCHEMBL669124 | 0.62 | ADRA2A (0.34) | GAA | |
| SCHEMBL28521977 | 0.60 | ALDH1A1 (0.30) | ALDH1A1MAPT | |
| SCHEMBL8964833 | 0.59 | POLB (0.33) | ALDH1A1MAPTHPGD | |
| SCHEMBL20613536 | 0.58 | — | — | |
| SCHEMBL1158351 | 0.58 | ALOX5 (0.42) | ALDH1A1GAAMAPTHPGDSMN1; SMN2 | |
| SCHEMBL25352415 | 0.55 | DAO (0.42) | ALDH1A1MAPTHPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0956294-B1 | THROMBIN INHIBITORS | ABBOTT GMBH & CO KG (DE) | 2004-06-09 | — | — | EP | disclosed |