Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 2/20 | 0.42 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8045554 | 0.90 | BACE1 (0.36) | ITGB3ITGA2BALOX15 | |
| SCHEMBL8783409 | 0.79 | ITGB3 (0.68) | ITGB3ITGA2BALOX15 | |
| SCHEMBL8783382 | 0.79 | ITGB3 (0.68) | ITGB3ITGA2BALOX15 | |
| Hydrochloric Acid SCHEMBL8783790 | 0.79 | ALOX15 (0.69) | ITGB3ITGA2BALOX15 | |
| Hydrochloric Acid SCHEMBL8034192 | 0.79 | ALOX15 (0.69) | ITGB3ITGA2BALOX15 | |
| SCHEMBL8052274 | 0.72 | ITGB3 (0.52) | ITGB3ITGA2BALOX15SLC18A3 | |
| SCHEMBL8045537 | 0.71 | ITGB3 (0.51) | ITGB3ITGA2BALOX15 | |
| SCHEMBL8783617 | 0.71 | POLB (0.46) | ITGB3ITGA2BALOX15SLC18A3 | |
| Hydrochloric Acid SCHEMBL8783744 | 0.69 | ALOX15 (0.66) | ITGB3ITGA2BALOX15 | |
| SCHEMBL8323744 | 0.69 | ITGB3 (0.65) | ITGB3ITGA2BALOX15MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6057324-A | HAVE GPIIB/IIIA RECEPTOR ANTAGONIZING ACTIVITY AND ARE USEFUL FOR AMELIORATING ISCHEMIC CARDIAC DISORDERS, FOR AMELIORATING CEREBROVASCULAR DISORDERS, AND FOR AMELIORATING PERIPHERAL ARTERY DISORDERS | YAMANOUCHI PHARMACEUTICAL CO., LTD (JP) | 2000-05-02 | — | — | US | disclosed |
| EP-0905129-A1 | SUBSTITUTED AMIDINOBENZENE DERIVATIVES AND MEDICINAL COMPOSITIONS THEREOF | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1999-03-31 | — | — | EP | disclosed |