Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.37 |
| ▸ | ESR1 | P03372 | 1/20 | 0.37 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.37 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.37 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | GGT1 | P19440 | 1/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 2/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.37 |
| ▸ | GBA1 | P04062 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7730049 | 0.86 | MAPT (0.44) | MAPK1KDM4EHSD17B10ALDH1A1TSHR | |
| SCHEMBL10569911 | 0.79 | ADRB2 (0.50) | MAPK1KDM4EHSD17B10ALDH1A1TSHR | |
| SCHEMBL2878709 | 0.79 | PRMT5 (0.40) | MAPK1KDM4EHSD17B10ALDH1A1TSHR | |
| SCHEMBL6687227 | 0.76 | MAPK1 (0.41) | MAPK1KDM4EHSD17B10ALDH1A1TSHR | |
| SCHEMBL7206062 | 0.75 | RXRA (0.50) | MAPK1KDM4EHSD17B10ALDH1A1TSHR | |
| SCHEMBL5734961 | 0.75 | DRD2 (0.46) | MAPK1KDM4EHSD17B10ALDH1A1TSHR | |
| SCHEMBL9404798 | 0.72 | MAPK1 (0.39) | MAPK1KDM4EHSD17B10ALDH1A1TSHR | |
| SCHEMBL17596594 | 0.72 | RXRA (0.50) | MAPK1KDM4EHSD17B10ALDH1A1TSHR | |
| SCHEMBL11805157 | 0.72 | MRGPRX4 (0.52) | MAPK1KDM4EHSD17B10ALDH1A1TSHR | |
| SCHEMBL5833456 | 0.71 | RXRA (0.49) | MAPK1KDM4EHSD17B10ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6130217-A | ANTITUMOR | PFIZER INC (US) | 2000-10-10 | — | — | US | disclosed |