Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 7/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 7/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 6/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 5/20 | 0.39 |
| ▸ | HDAC10 | Q969S8 | 5/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 4/20 | 0.39 |
| ▸ | HDAC7 | Q8WUI4 | 4/20 | 0.39 |
| ▸ | HDAC11 | Q96DB2 | 4/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.39 |
| ▸ | HDAC9 | Q9UKV0 | 4/20 | 0.39 |
| ▸ | HDAC5 | Q9UQL6 | 4/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.37 |
| ▸ | KCNA3 | P22001 | 3/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8049747 | 0.92 | CYP3A4 (0.43) | KMT2AALDH1A1POLBMAPTHDAC3 | |
| SCHEMBL8044655 | 0.92 | CYP3A4 (0.43) | KMT2AALDH1A1POLBMAPTHDAC3 | |
| SCHEMBL8044657 | 0.90 | CCR1 (0.43) | KMT2AALDH1A1POLBMAPTHDAC3 | |
| SCHEMBL8035617 | 0.89 | KMT2A (0.40) | KMT2AALDH1A1POLBMAPTHDAC3 | |
| SCHEMBL8433999 | 0.84 | ALDH1A1 (0.46) | ALDH1A1MAPTHDAC3HDAC1HDAC2 | |
| SCHEMBL8050105 | 0.84 | HDAC3 (0.38) | KMT2AALDH1A1HDAC3HDAC1HDAC2 | |
| SCHEMBL8047487 | 0.82 | HDAC6 (0.42) | HDAC3HDAC1HDAC2HDAC8HDAC10 | |
| SCHEMBL8044965 | 0.80 | OPRM1 (0.43) | HDAC6KCNA3RAB9ACYP3A4CYP2C9 | |
| SCHEMBL8045183 | 0.80 | OPRM1 (0.43) | HDAC6KCNA3RAB9ACYP3A4CYP2C9 | |
| SCHEMBL8045631 | 0.79 | HDAC6 (0.39) | KMT2AALDH1A1POLBMAPTHDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0749957-B1 | Aromatic hydroxamic acid compounds, their production and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2000-04-26 | — | — | EP | disclosed |
| US-5891916-A | ANTINEUROGEGERATIVE AGENT | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1999-04-06 | — | — | US | disclosed |
| EP-0749957-A1 | Aromatic hydroxamic acid compounds, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1996-12-27 | — | — | EP | disclosed |