Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGD | P52209 | 3/20 | 0.38 |
| ▸ | LPAR5 | Q9H1C0 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | ANPEP | P15144 | 2/20 | 0.37 |
| ▸ | ERAP2 | Q6P179 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | PGK1 | P00558 | 1/20 | 0.36 |
| ▸ | PGK2 | P07205 | 1/20 | 0.36 |
| ▸ | MMP2 | P08253 | 4/20 | 0.35 |
| ▸ | CA12 | O43570 | 2/20 | 0.35 |
| ▸ | CA1 | P00915 | 2/20 | 0.35 |
| ▸ | CA2 | P00918 | 2/20 | 0.35 |
| ▸ | CA9 | Q16790 | 2/20 | 0.35 |
| ▸ | MMP1 | P03956 | 2/20 | 0.35 |
| ▸ | MMP8 | P22894 | 1/20 | 0.35 |
| ▸ | MMP3 | P08254 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9280697 | 1.00 | PGD (0.38) | PGDLPAR5ALDH1A1HSD17B10ANPEP | |
| Glycerin SCHEMBL6518227 | 0.83 | ALDH1A1 (0.46) | ALDH1A1HSD17B10ANPEPERAP2KDM4E | |
| SCHEMBL14278848 | 0.79 | PGK1 (0.52) | PGDLPAR5ALDH1A1PGK1PGK2 | |
| SCHEMBL7340 | 0.79 | PGK1 (0.52) | PGDLPAR5ALDH1A1PGK1PGK2 | |
| SCHEMBL213379 | 0.79 | PGK1 (0.52) | PGDLPAR5ALDH1A1PGK1PGK2 | |
| SCHEMBL7341 | 0.79 | PGK1 (0.52) | PGDLPAR5ALDH1A1PGK1PGK2 | |
| SCHEMBL14278847 | 0.79 | PGK1 (0.52) | PGDLPAR5ALDH1A1PGK1PGK2 | |
| SCHEMBL6655023 | 0.79 | PGK1 (0.52) | PGDLPAR5ALDH1A1PGK1PGK2 | |
| SCHEMBL468639 | 0.77 | PGK1 (0.50) | PGDLPAR5PGK1PGK2MPI | |
| Water SCHEMBL11070947 | 0.77 | PGK1 (0.50) | PGDLPAR5PGK1PGK2MPI |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10575520-B2 | Cyclohexylamine-based compounds and uses thereof | BOARD OF SUPERVISORS OF LOUISIANA STATE UNIVERSITY AND AGRICULTURAL AND MECHANICAL COLLEGE (US) | 2020-03-03 | — | — | US | disclosed |
| US-20170265464-A1 | CYCLOHEXYLAMINE-BASED COMPOUNDS AND USES THEREOF | BOARD OF SUPERVISORS OF LOUISIANA STATE UNIVERSITY AND AGRICULTURAL AND MECHANICAL COLLEGE | 2017-09-21 | — | — | US | disclosed |
| US-6015573-A | TREATMENT OF RESISTANT HERPES VIRUS WITH NUCLEOSIDE PHOSPHATE ESTERS | RESOLUTION PERFORMANCE PRODUCTS LLC | 2000-01-18 | — | — | US | disclosed |
| US-5879700-A | TREATING HERPES VIRUS INFECTIONS | HOSTETLER KARL Y (US) | 1999-03-09 | — | — | US | disclosed |
| EP-0831794-A4 | ACYCLOVIR DERIVATIVES FOR TOPICAL USE | HOSTETLER KARL Y (US) | 1998-11-04 | — | — | EP | disclosed |
| US-5756116-A | VIRICIDES USING ACYCLOVIR RESISTANT STRAIN OF HERPES VIRUS | HOSTETLER KARL Y (US) | 1998-05-26 | — | — | US | disclosed |
| EP-0831794-A1 | ACYCLOVIR DERIVATIVES FOR TOPICAL USE | HOSTETLER, Karl Y. (US) | 1998-04-01 | — | — | EP | disclosed |
| EP-0746319-A4 | ACYCLOVIR DERIVATIVES FOR TOPICAL USE | HOSTETLER KARL Y (US) | 1997-11-05 | — | — | EP | disclosed |
| WO-1996040088-A1 | ACYCLOVIR DERIVATIVES FOR TOPICAL USE | HOSTETLER KARL Y (US) | 1996-12-19 | — | — | WO | disclosed |
| EP-0746319-A1 | ACYCLOVIR DERIVATIVES FOR TOPICAL USE | HOSTETLER, Karl Y. (US) | 1996-12-11 | — | — | EP | disclosed |
| US-5580571-A | ACYCLOIR MONO OR DIPHOSPHATE; TOPICAL USE IN HERPES VIRUSINFECTIONS | HOSTETLER KARL Y (US) | 1996-12-03 | — | — | US | disclosed |
| WO-1994026273-A1 | ACYCLOVIR DERIVATIVES FOR TOPICAL USE | HOSTETLER KARL Y (US) | 1994-11-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170265464-A1 | CYCLOHEXYLAMINE-BASED COMPOUNDS AND USES THEREOF | HNRNPA2B1, NOP2, HCRTR2 | PGD 4812/4885LPAR5 690/4885ALDH1A1 3213/4885 |
| US-10575520-B2 | Cyclohexylamine-based compounds and uses thereof | HNRNPA2B1, NOP2, HCRTR2 | PGD 4812/4885LPAR5 690/4885ALDH1A1 3213/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.