Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FPR2 | P25090 | 3/20 | 0.33 |
| ▸ | MMP3 | P08254 | 1/20 | 0.30 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8249283 | 0.86 | TERF2 (0.35) | FPR2 | |
| SCHEMBL12608361 | 0.83 | CTSV (0.35) | — | |
| SCHEMBL13685078 | 0.83 | CTSV (0.35) | — | |
| SCHEMBL8290299 | 0.83 | CTSV (0.35) | — | |
| SCHEMBL16349686 | 0.78 | CTSV (0.33) | — | |
| SCHEMBL16349671 | 0.78 | CTSV (0.33) | — | |
| SCHEMBL8257249 | 0.75 | PSMB9 (0.31) | — | |
| SCHEMBL13685337 | 0.74 | CTSV (0.34) | — | |
| SCHEMBL13685005 | 0.74 | CTSV (0.34) | — | |
| SCHEMBL13685690 | 0.72 | CTSV (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009058856-A1 | MACROCYCLIC INHIBITORS OF HEPATITIS C VIRUS NS3 SERINE PROTEASE | SCHERING CORPORATION (US) | 2009-05-07 | — | — | WO | disclosed |