Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMB9 | P28065 | 5/20 | 0.31 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.31 |
| ▸ | TERF2 | Q15554 | 3/20 | 0.31 |
| ▸ | HDAC4 | P56524 | 6/20 | 0.30 |
| ▸ | HDAC1 | Q13547 | 6/20 | 0.30 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.30 |
| ▸ | PPIA | P62937 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16298069 | 0.90 | — | — | |
| SCHEMBL8249283 | 0.87 | TERF2 (0.35) | TERF2HDAC4HDAC1HDAC6 | |
| SCHEMBL13685005 | 0.86 | CTSV (0.34) | — | |
| SCHEMBL13685337 | 0.86 | CTSV (0.34) | — | |
| SCHEMBL16349620 | 0.81 | CTSV (0.32) | — | |
| SCHEMBL8290299 | 0.75 | CTSV (0.35) | — | |
| SCHEMBL12608361 | 0.75 | CTSV (0.35) | — | |
| SCHEMBL13685078 | 0.75 | CTSV (0.35) | — | |
| SCHEMBL8053236 | 0.75 | FPR2 (0.33) | — | |
| SCHEMBL8291443 | 0.74 | F2 (0.43) | TERF2HDAC4HDAC1HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005030796-A1 | MACROCYCLIC INHIBITORS OF HEPATITIS C VIRUS NS3 SERINE PROTEASE | SCHERING CORPORATION (US) | 2005-04-07 | — | — | WO | disclosed |