Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 2/20 | 0.43 |
| ▸ | SRC | P12931 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CES2 | O00748 | 1/20 | 0.40 |
| ▸ | CES1 | P23141 | 1/20 | 0.40 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.40 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16738658 | 0.85 | ALDH1A1 (0.48) | HPGDL3MBTL1LMNAMAPK1KMT2A | |
| SCHEMBL10352549 | 0.84 | RXRA (0.51) | — | |
| SCHEMBL173884 | 0.83 | L3MBTL1 (0.43) | CYP2D6SRCCYP1A2ATML3MBTL1 | |
| SCHEMBL2439193 | 0.81 | L3MBTL1 (0.42) | CYP2D6SRCHPGDATML3MBTL1 | |
| Acetic Acid SCHEMBL27497152 | 0.81 | CYP2D6 (0.41) | CYP2D6SRCHPGDATML3MBTL1 | |
| SCHEMBL60355 | 0.81 | KMT2A (0.42) | CYP2D6SRCCYP1A2ATML3MBTL1 | |
| SCHEMBL2439196 | 0.81 | L3MBTL1 (0.42) | CYP2D6SRCHPGDATML3MBTL1 | |
| SCHEMBL2439195 | 0.81 | L3MBTL1 (0.42) | CYP2D6SRCHPGDATML3MBTL1 | |
| SCHEMBL23357274 | 0.80 | CYP2D6 (0.44) | CYP2D6SRCCYP1A2LMNAMAPK1 | |
| SCHEMBL6752757 | 0.80 | CYP2D6 (0.44) | CYP2D6SRCHPGDATML3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0820439-B1 | METHOD FOR THE ASYMMETRICAL SYNTHESIS OF S-ACYLATED DERIVATIVES OF 2-MERCAPTOMETHYL 3-PHENYL PROPANOIC ACID, AND USE THEREOF FOR SYNTHESISING N-(MERCAPTOACYL) AMINO ACID DERIVATIVES | BIOPROJET SOC CIV (FR) | 2000-05-03 | — | — | EP | claimed |
| EP-0491538-A1 | Stereocontrolled production of hydroxyester, hydroxyamide, and lactone compounds from chiral alpha-amino aldehydes | MERCK & CO. INC. (US) | 1992-06-24 | — | — | EP | disclosed |
| EP-0019578-B1 | PIPERIDINE DERIVATIVES, PROCESS FOR PREPARING THEM AND POLYMER COMPOSITIONS CONTAINING THEM | Chimosa Chimica Organica S.p.A. (IT) | 1983-03-30 | — | — | EP | disclosed |
| EP-0019578-A1 | Piperidine derivatives, process for preparing them and polymer compositions containing them | Chimosa Chimica Organica S.p.A. (IT) | 1980-11-26 | — | — | EP | disclosed |