Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | EDNRB | P24530 | 2/20 | 0.42 |
| ▸ | EDNRA | P25101 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | CASP7 | P55210 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16831449 | 0.80 | RECQL (0.53) | NPSR1EDNRAMAPTKDM4ECYP1A2 | |
| SCHEMBL30569541 | 0.78 | MAPT (0.43) | L3MBTL1ALDH1A1SMN1; SMN2NPSR1TP53 | |
| SCHEMBL29070085 | 0.78 | MAPT (0.43) | L3MBTL1ALDH1A1SMN1; SMN2NPSR1TP53 | |
| SCHEMBL4806739 | 0.76 | SIGMAR1 (0.54) | ALDH1A1SMN1; SMN2GAATSHRMAPK1 | |
| SCHEMBL197038 | 0.75 | ALDH1A1 (0.49) | ALDH1A1GLASMN1; SMN2EDNRBEDNRA | |
| SCHEMBL26921226 | 0.75 | ALDH1A1 (0.46) | ALDH1A1GLASMN1; SMN2NPSR1EDNRB | |
| SCHEMBL18706988 | 0.75 | ALDH1A1 (0.49) | ALDH1A1GLASMN1; SMN2NPSR1EDNRB | |
| SCHEMBL8056804 | 0.74 | CTSL (0.48) | ALDH1A1GLASMN1; SMN2EDNRBEDNRA | |
| SCHEMBL8060863 | 0.72 | ALDH1A1 (0.52) | ALDH1A1GLASMN1; SMN2MAPTGAA | |
| SCHEMBL198379 | 0.71 | RECQL (0.69) | L3MBTL1ALDH1A1GLASMN1; SMN2EDNRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009026197-A1 | NOVEL CATHEPSIN C INHIBITORS AND THEIR USE | GLAXO GROUP LIMITED (GB) | 2009-02-26 | — | — | WO | disclosed |