Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 2/20 | 0.48 |
| ▸ | CTSS | P25774 | 2/20 | 0.48 |
| ▸ | CTSK | P43235 | 2/20 | 0.48 |
| ▸ | CTSC | P53634 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | CTSB | P07858 | 1/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | EDNRB | P24530 | 2/20 | 0.45 |
| ▸ | EDNRA | P25101 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13663732 | 0.81 | RECQL (0.45) | CTSLCTSSCTSKCTSCALDH1A1 | |
| SCHEMBL197038 | 0.79 | ALDH1A1 (0.49) | CTSLCTSSCTSKCTSCALDH1A1 | |
| SCHEMBL20451437 | 0.76 | SIGMAR1 (0.54) | CA1CA2GAA | |
| SCHEMBL26921226 | 0.75 | ALDH1A1 (0.46) | ALDH1A1GLASMN1; SMN2EDNRBEDNRA | |
| SCHEMBL18706988 | 0.75 | ALDH1A1 (0.49) | CTSLCTSSCTSKCTSCALDH1A1 | |
| SCHEMBL8060863 | 0.75 | ALDH1A1 (0.52) | ALDH1A1GLASMN1; SMN2KMT2AMEN1 | |
| SCHEMBL8053790 | 0.74 | L3MBTL1 (0.47) | CTSLCTSSCTSKALDH1A1CTSB | |
| SCHEMBL16333682 | 0.74 | ATM (0.56) | CTSLCTSSCTSKCTSCALDH1A1 | |
| SCHEMBL198379 | 0.74 | RECQL (0.69) | ALDH1A1GLASMN1; SMN2EDNRBEDNRA | |
| SCHEMBL196418 | 0.74 | RECQL (0.69) | ALDH1A1GLASMN1; SMN2EDNRBEDNRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009026197-A1 | NOVEL CATHEPSIN C INHIBITORS AND THEIR USE | GLAXO GROUP LIMITED (GB) | 2009-02-26 | — | — | WO | disclosed |