Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | XDH | P47989 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | GFER | P55789 | 1/20 | 0.46 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.46 |
| ▸ | RELA | Q04206 | 1/20 | 0.46 |
| ▸ | FUT7 | Q11130 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 4/20 | 0.43 |
| ▸ | CA2 | P00918 | 4/20 | 0.43 |
| ▸ | CA12 | O43570 | 3/20 | 0.43 |
| ▸ | CA7 | P43166 | 3/20 | 0.43 |
| ▸ | CA9 | Q16790 | 3/20 | 0.43 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12807357 | 0.85 | KDM4E (0.57) | GAAKDM4ETDP1LMNAXDH | |
| SCHEMBL8308995 | 0.84 | TNFRSF1A (0.43) | GAAKDM4ETDP1LMNAXDH | |
| SCHEMBL755528 | 0.84 | GAA (0.59) | GAAKDM4ETDP1LMNAXDH | |
| SCHEMBL2240647 | 0.80 | NOTUM (0.48) | GAAKDM4ETDP1LMNAXDH | |
| SCHEMBL1406483 | 0.80 | GAA (0.50) | GAAKDM4ETDP1LMNAXDH | |
| SCHEMBL10268453 | 0.78 | ALOX5 (0.43) | GAAKDM4ETDP1LMNACA1 | |
| SCHEMBL30924510 | 0.78 | GAA (0.52) | GAAKDM4ETDP1LMNAXDH | |
| SCHEMBL24821894 | 0.76 | GAA (0.50) | GAAKDM4ETDP1LMNAXDH | |
| SCHEMBL14216739 | 0.75 | ALDH1A1 (0.44) | GAATDP1LMNAPOLBCA2 | |
| SCHEMBL14216738 | 0.75 | CNR2 (0.43) | GAATDP1LMNAALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 48 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8399073-B2 | Liquid-crystal medium | MERCK Patent Gesellschaft mit beschränkter Haftung (DE) | 2013-03-19 | — | — | US | disclosed |
| US-20130056680-A1 | LIQUID CRYSTALLINE MEDIUM AND LIQUID CRYSTAL DISPLAY | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2013-03-07 | — | — | US | disclosed |
| US-8349415-B2 | Liquid-crystalline medium and liquid-crystal display having high twist | MERCK Patent Gesellschaft mit beschränkter Haftung (DE) | 2013-01-08 | — | — | US | disclosed |
| US-20120326085-A1 | LIQUID-CRYSTALLINE MEDIUM | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2012-12-27 | — | — | US | disclosed |
| US-20120326084-A1 | LIQUID-CRYSTALLINE MEDIUM | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2012-12-27 | — | — | US | disclosed |
| US-20120268706-A1 | COMPOUNDS AND LIQUID-CRYSTALLINE MEDIUM | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2012-10-25 | — | — | US | disclosed |
| US-20120248374-A1 | LIQUID CRYSTALLINE MEDIUM | MERCK PATENT GMBH (DE) | 2012-10-04 | — | — | US | disclosed |
| US-8277684-B2 | Liquid-crystal medium | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2012-10-02 | — | — | US | disclosed |
| US-20120228549-A1 | LIQUID-CRYSTALLINE MEDIUM | MERCK PATENT GMBH (DE) | 2012-09-13 | — | — | US | disclosed |
| US-20120224124-A1 | POLYMERIZABLE COMPOUNDS AND THE USE THEREOF IN LIQUID CRYSTAL DISPLAYS | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2012-09-06 | — | — | US | disclosed |
| US-7425355-B2 | Liquid-crystalline medium | MERCK PATENT GMBH (DE) | 2008-09-16 | — | — | US | disclosed |
| US-20080193681-A1 | Liquid-Crystal Medium | MERCK PATENT GMBH (DE) | 2008-08-14 | — | — | US | disclosed |
| US-7361288-B2 | Components for high-frequency technology | MERCK PATENT GESELLSCHAFT MIT BESSCHRANKTER HAFTUNG (DE) | 2008-04-22 | — | — | US | disclosed |
| US-20080088789-A1 | Liquid-crystalline medium | MERCK PATENT GMBH | 2008-04-17 | — | — | US | disclosed |
| US-7351453-B2 | Mixture of polar compounds of biphenyls, cyclohexane and phenyl substituted biphenyl; fast response time, a low threshold voltage, low temperature stability | MERCK PATENT GMBH (DE) | 2008-04-01 | — | — | US | disclosed |
| US-7344761-B2 | Liquid-crystalline compounds | MERCK PATENT GESELLASCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2008-03-18 | — | — | US | disclosed |
| US-7335403-B2 | Liquid-crystalline medium | MERCK PATENT GMBH (DE) | 2008-02-26 | — | — | US | disclosed |
| US-20070269614-A1 | Containing at least two nitrile-free mesogenic compounds, one of which contains rings including a phenyl ring llinked by at least one -CF2O- group; electrooptical dispalys | HECKMEIER MICHAEL | 2007-11-22 | — | — | US | disclosed |
| US-20070080324-A1 | mixture of polar compounds of negative dielectric anisotropy; electro-optical display with active-matrix addressing based on the ECB(electrically controlled birefringence), PALC (positive charge assisted leakage current) or IPS ( in plane switching) effect | MERCK PATENT GMBH (DE) | 2007-04-12 | — | — | US | disclosed |
| US-20070034828-A1 | Containing 3 directly connected rings: a fluorophenyl ring, a tetrahydropyran ring and either another tetrahydropyran ring or a 1,3-dioxane ring; electrooptical displays; | MERCK PATENT GMBH (DE) | 2007-02-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120326084-A1 | LIQUID-CRYSTALLINE MEDIUM | NEFM, VIM, PLG | GAA 2524/4885KDM4E 3104/4885TDP1 1510/4885 |
| US-20120248374-A1 | LIQUID CRYSTALLINE MEDIUM | LBR, CTNND1, VIM | GAA 3873/4885KDM4E 4448/4885TDP1 2053/4885 |
| US-20120268706-A1 | COMPOUNDS AND LIQUID-CRYSTALLINE MEDIUM | NEFM, VIM, FLNB | GAA 4098/4885KDM4E 3089/4885TDP1 2064/4885 |
| US-20120326085-A1 | LIQUID-CRYSTALLINE MEDIUM | TLL1, LAS1L, LOXL1 | GAA 2992/4885KDM4E 4139/4885TDP1 2329/4885 |
| US-20120224124-A1 | POLYMERIZABLE COMPOUNDS AND THE USE THEREOF IN LIQUID CRYSTAL DISPLAYS | VCL, LPXN, LCP1 | GAA 3052/4885KDM4E 3333/4885TDP1 2659/4885 |
| US-20080088789-A1 | Liquid-crystalline medium | F12, CHRM1, NEFM | GAA 1863/4885KDM4E 4803/4885TDP1 1742/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.