Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FBP1 | P09467 | 11/20 | 0.50 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.45 |
| ▸ | PNP | P00491 | 1/20 | 0.39 |
| ▸ | FDPS | P14324 | 1/20 | 0.39 |
| ▸ | MGAM | O43451 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | SI | P14410 | 2/20 | 0.38 |
| ▸ | MGAM2 | Q2M2H8 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6630237 | 0.76 | SIRT1 (0.53) | FBP1PDK1FDPSMGAMGAA | |
| SCHEMBL27271796 | 0.76 | ALDH1A1 (0.47) | FBP1PDK1FDPSMGAMGAA | |
| SCHEMBL10395763 | 0.75 | FBP1 (0.46) | FBP1PDK1MGAMGAASI | |
| Hydrochloric Acid SCHEMBL10395358 | 0.73 | ALDH1A1 (0.47) | FBP1PDK1MGAMGAASI | |
| SCHEMBL7114230 | 0.73 | FBP1 (0.70) | FBP1PDK1FDPSALDH1A1 | |
| SCHEMBL2982080 | 0.73 | FBP1 (0.52) | FBP1PDK1MGAMGAASI | |
| SCHEMBL28177930 | 0.72 | FBP1 (0.59) | FBP1PDK1MGAMGAASI | |
| SCHEMBL11205285 | 0.71 | ALOX15 (0.53) | PNPGAASMN1; SMN2RAB9AALDH1A1 | |
| SCHEMBL31339525 | 0.71 | ALOX15 (0.53) | PNPGAASMN1; SMN2RAB9AALDH1A1 | |
| SCHEMBL69003 | 0.71 | ALOX15 (0.53) | PNPGAASMN1; SMN2RAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6130217-A | ANTITUMOR | PFIZER INC (US) | 2000-10-10 | — | — | US | disclosed |
| WO-1994022846-A1 | COMPOUNDS ENHANCING ANTITUMOR ACTIVITY OF OTHER CYTOTOXIC AGENTS | PFIZER INC. (US) | 1994-10-13 | — | — | WO | disclosed |
| US-4865641-A | Herbicidal new thiazolyl ether and thioether derivatives | BAYER AKTIENGESELLSCHAFT (DE) | 1989-09-12 | — | — | US | disclosed |
| EP-0281907-A1 | Thiazolyl ether and thioether derivatives | BAYER AG (DE) | 1988-09-14 | — | — | EP | disclosed |