Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | NOS1 | P29475 | 1/20 | 0.34 |
| ▸ | ADH1B | P00325 | 1/20 | 0.31 |
| ▸ | ADH1C | P00326 | 1/20 | 0.31 |
| ▸ | ADH1A | P07327 | 1/20 | 0.31 |
| ▸ | ADH7 | P40394 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22188405 | 0.81 | — | — | |
| SCHEMBL20744051 | 0.76 | ALDH1A1 (0.30) | ALDH1A1 | |
| SCHEMBL3246801 | 0.75 | NOS1 (0.39) | OPRM1SLC6A3NOS1NPC1RAB9A | |
| SCHEMBL5898085 | 0.74 | — | — | |
| SCHEMBL14516134 | 0.74 | OPRM1 (0.40) | OPRM1SLC6A3NOS1NPC1RAB9A | |
| SCHEMBL621509 | 0.74 | SLC6A3 (0.39) | OPRM1SLC6A3NOS1 | |
| SCHEMBL7497015 | 0.73 | GAA (0.50) | NPC1RAB9AALDH1A1GAA | |
| SCHEMBL12808356 | 0.72 | NOS1 (0.37) | OPRM1SLC6A3NOS1NPC1RAB9A | |
| SCHEMBL20743897 | 0.71 | — | — | |
| SCHEMBL28087107 | 0.69 | SLC6A3 (0.36) | OPRM1SLC6A3NOS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0669336-B1 | NOVEL CEPHEM DERIVATIVES | MEIJI SEIKA CO (JP) | 2000-05-17 | — | — | EP | disclosed |
| US-5663162-A | BACTERICIDES AND ANTIBIOTICS | MEIJI SEIKA KABUSHIKI KAISHA (JP) | 1997-09-02 | — | — | US | disclosed |
| EP-0669336-A1 | NOVEL CEPHEM DERIVATIVE | MEIJI SEIKA KABUSHIKI KAISHA (JP) | 1995-08-30 | — | — | EP | disclosed |