Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.43 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 4/20 | 0.42 |
| ▸ | HPGD | P15428 | 4/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.42 |
| ▸ | GLA | P06280 | 3/20 | 0.42 |
| ▸ | CASP1 | P29466 | 2/20 | 0.42 |
| ▸ | CASP7 | P55210 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | HTR2B | P41595 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8052787 | 0.73 | ATM (0.38) | KDM4ETDP1ALDH1A1GAAHPGD | |
| SCHEMBL5248011 | 0.71 | ATM (0.48) | KDM4EMAPTTDP1ALDH1A1HPGD | |
| SCHEMBL4624598 | 0.70 | KDM4E (0.51) | KDM4EMAPTTDP1ALDH1A1ADRB2 | |
| SCHEMBL4423477 | 0.70 | ATM (0.48) | KDM4EMAPTALDH1A1GAAHPGD | |
| SCHEMBL30517750 | 0.70 | KDM4E (0.50) | KDM4EMAPTTDP1ALDH1A1ADRB2 | |
| SCHEMBL7109825 | 0.68 | MAPT (0.57) | KDM4EMAPTTDP1ALDH1A1ADRB2 | |
| SCHEMBL6015960 | 0.68 | ALDH1A1 (0.43) | KDM4EMAPTTDP1ALDH1A1ADRB2 | |
| SCHEMBL4623327 | 0.67 | ALDH1A1 (0.53) | KDM4EMAPTTDP1ALDH1A1ADRB2 | |
| SCHEMBL2233013 | 0.67 | ADRB2 (0.60) | KDM4EMAPTTDP1ALDH1A1ADRB2 | |
| SCHEMBL28135724 | 0.67 | CYP3A4 (0.38) | KDM4EMAPTTDP1ALDH1A1ADRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0428442-B1 | Composition comprising derivatives of 6- or 7-hydroxyindole as couplers and dyeing processes using same | OREAL (FR) | 1994-08-31 | — | — | EP | claimed |
| CN-1051727-A | Use 6-or 7-hydroxy indoxyl derivative as chromogenic reagent, contain the composition of this derivative and the staining of carrying out with said composition | OREAL (FR) | 1991-05-29 | — | — | CN | claimed |
| EP-0428442-A1 | Composition comprising derivatives of 6- or 7-hydroxyindole as couplers and dyeing processes using same | L'OREAL (FR) | 1991-05-22 | — | — | EP | claimed |
| US-6090160-A | USE OF THE 6- OR 7-HYDROXYINDOLE COUPLER ENABLES DYEINGS WITH RESISTANCE TO LIGHT, TO WASHING, TO THE WEATHER AND TO PERSPIRATION TO BE OBTAINED, IN PARTICULAR WHEN USED WITH P-PHENYLENEDIAMINE DERIVATIVES | L'OREAL (FR) | 2000-07-18 | — | — | US | disclosed |
| EP-0428442-B1 | Composition comprising derivatives of 6- or 7-hydroxyindole as couplers and dyeing processes using same | OREAL (FR) | 1994-08-31 | — | — | EP | disclosed |
| CN-1051727-A | Use 6-or 7-hydroxy indoxyl derivative as chromogenic reagent, contain the composition of this derivative and the staining of carrying out with said composition | OREAL (FR) | 1991-05-29 | — | — | CN | disclosed |
| EP-0428442-A1 | Composition comprising derivatives of 6- or 7-hydroxyindole as couplers and dyeing processes using same | L'OREAL (FR) | 1991-05-22 | — | — | EP | disclosed |