Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.51 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.49 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | NPY1R | P25929 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | AKT1 | P31749 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 4/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1993443 | 0.83 | BCHE (0.40) | ALDH1A1PKMKDM4EMAPTTDP1 | |
| SCHEMBL31543744 | 0.80 | P2RX7 (0.41) | ALDH1A1PKMKDM4EHSD17B10GAA | |
| SCHEMBL28017334 | 0.80 | P2RX7 (0.41) | ALDH1A1PKMKDM4EHSD17B10GAA | |
| SCHEMBL1400453 | 0.77 | MTNR1A (0.40) | ALDH1A1PKMKDM4EKMT2AMEN1 | |
| SCHEMBL3617254 | 0.77 | MTNR1A (0.53) | ALDH1A1KDM4EMAPTKMT2AMEN1 | |
| SCHEMBL8915154 | 0.76 | ALDH1A1 (0.45) | ALDH1A1PKMKDM4EMAPTTDP1 | |
| SCHEMBL3621271 | 0.74 | ALDH1A1 (0.42) | ALDH1A1PKMKDM4EMAPTKMT2A | |
| SCHEMBL7833443 | 0.73 | ADRB2 (0.54) | ALDH1A1PKMKDM4EMAPTTDP1 | |
| SCHEMBL6804682 | 0.73 | HTR1D (0.36) | ALDH1A1PKMKDM4EADRB2HSD17B10 | |
| SCHEMBL4624598 | 0.72 | KDM4E (0.51) | ALDH1A1PKMKDM4EMAPTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0446131-B1 | Keratinous fibres dyeing process with substituted monohydroxy indols and compositions | OREAL (FR) | 1994-05-04 | — | — | EP | claimed |
| EP-0446131-A1 | Keratinous fibres dyeing process with substituted monohydroxy indols and compositions | L'OREAL (FR) | 1991-09-11 | — | — | EP | claimed |
| EP-1067950-B1 | NEO-TRYPTOPHAN | MAYO FOUNDATION (US) | 2008-05-14 | — | — | EP | disclosed |
| CN-1344270-A | Functionalized heterocycles as chemokine receptor modulators | THOUSAND YEARS MEDICAMENTS INC (US) | 2002-04-10 | — | — | CN | disclosed |
| EP-1144415-A2 | FUNCTIONALIZED HETEROCYCLES AS CHEMOKINE RECEPTOR MODULATORS | WARNER-LAMBERT COMPANY (US) | 2001-10-17 | — | — | EP | disclosed |
| WO-2000042045-A2 | FUNCTIONALIZED HETEROCYCLES AS CHEMOKINE RECEPTOR MODULATORS | WARNER-LAMBERT COMPANY (US) | 2000-07-20 | — | — | WO | disclosed |
| EP-0446131-B1 | Keratinous fibres dyeing process with substituted monohydroxy indols and compositions | OREAL (FR) | 1994-05-04 | — | — | EP | disclosed |
| EP-0446131-A1 | Keratinous fibres dyeing process with substituted monohydroxy indols and compositions | L'OREAL (FR) | 1991-09-11 | — | — | EP | disclosed |