Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 5/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.32 |
| ▸ | NPC1 | O15118 | 4/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.32 |
| ▸ | HTT | P42858 | 4/20 | 0.32 |
| ▸ | RAB9A | P51151 | 4/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.32 |
| ▸ | MEN1 | O00255 | 3/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.32 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6526712 | 0.86 | TLR8 (0.42) | TLR8GAAKDM4ENPC1ALDH1A1 | |
| SCHEMBL29447338 | 0.84 | ALDH1A1 (0.39) | ALDH1A1TDP1MAPT | |
| SCHEMBL3955072 | 0.84 | ALDH1A1 (0.39) | ALDH1A1TDP1MAPT | |
| SCHEMBL29695262 | 0.83 | ALDH1A1 (0.38) | ALDH1A1TDP1MAPT | |
| SCHEMBL8059198 | 0.83 | TLR8 (0.35) | TLR8GAAKDM4ENPC1ALDH1A1 | |
| Potassium SCHEMBL29695394 | 0.81 | WDR5 (0.37) | ALDH1A1TDP1MAPT | |
| SCHEMBL8020132 | 0.79 | CYP2A6 (0.41) | ALDH1A1TDP1CYP1A2HPGDMAPT | |
| SCHEMBL8056374 | 0.78 | MAPT (0.33) | ALDH1A1TDP1MAPT | |
| SCHEMBL8055036 | 0.77 | TSHR (0.32) | NPC1ALDH1A1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL8927613 | 0.77 | WDR5 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0704449-B1 | Process for the preparation of diphosphanes | CELANESE CHEM EUROPE GMBH (DE) | 2000-05-24 | — | — | EP | disclosed |
| US-5696296-A | Diphosphines and process for their preparation | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-12-09 | — | — | US | disclosed |
| EP-0704449-A1 | Diphosphanes and process for their preparation | HOECHST AKTIENGESELLSCHAFT (DE) | 1996-04-03 | — | — | EP | disclosed |