SCHEMBL8927613

SCHEMBL8927613

C=CCP(CC=C)Cc1ccc2ccccc2c1-c1c(CP(c2ccccc2)c2ccccc2)ccc2ccccc12

nearest known ligand 0.39

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
WDR5 P61964 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3955072 0.85 ALDH1A1 (0.39) WDR5
SCHEMBL29447338 0.85 ALDH1A1 (0.39) WDR5
SCHEMBL29695262 0.84 ALDH1A1 (0.38) WDR5
Potassium SCHEMBL29695394 0.82 WDR5 (0.37) WDR5
SCHEMBL8056374 0.79 MAPT (0.33) WDR5
SCHEMBL8927612 0.78
SCHEMBL8055032 0.77 TLR8 (0.34)
SCHEMBL8020132 0.77 CYP2A6 (0.41) WDR5
SCHEMBL8056031 0.77 CES1 (0.36) WDR5
SCHEMBL9014995 0.76 WDR5 (0.33) WDR5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5684182-A Sulfonated diphosphines and a process for their preparation HOECHST AKTIENGESELLSCHAFT (DE) 1997-11-04 US disclosed