SCHEMBL8057744

SCHEMBL8057744

Cc1ccccc1NC(=S)c1ccc(C2(F)CC2c2ccc(Br)c(Br)c2)cc1

nearest known ligand 0.36

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.36
L3MBTL1 Q9Y468 4/20 0.36
KMT2A Q03164 4/20 0.36
LMNA P02545 3/20 0.36
MEN1 O00255 3/20 0.36
MAPT P10636 3/20 0.35
RAB9A P51151 3/20 0.35
NPC1 O15118 2/20 0.34
NPSR1 Q6W5P4 1/20 0.34
GAA P10253 2/20 0.34
EPHX1 P07099 2/20 0.33
CYP2C19 P33261 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8038471 0.88 NPC1 (0.46) ALDH1A1L3MBTL1KMT2ALMNAMEN1
SCHEMBL8042055 0.78 S1PR4 (0.40)
SCHEMBL8463202 0.75 MAPT (0.43) ALDH1A1KMT2ALMNAMEN1MAPT
SCHEMBL8055080 0.75 GPBAR1 (0.35) ALDH1A1
SCHEMBL8057747 0.73 LMNA (0.49) ALDH1A1L3MBTL1KMT2ALMNAMEN1
SCHEMBL8040665 0.73 POLB (0.56) ALDH1A1L3MBTL1KMT2ALMNAMEN1
SCHEMBL8057743 0.70 LMNA (0.47) ALDH1A1L3MBTL1KMT2ALMNAMEN1
SCHEMBL9191694 0.68 MMP1 (0.40) ALDH1A1KMT2ALMNAMEN1MAPT
SCHEMBL9190956 0.68 MMP1 (0.40) ALDH1A1KMT2ALMNAMEN1MAPT
SCHEMBL9191690 0.68 MMP1 (0.40) ALDH1A1KMT2ALMNAMEN1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0805795-A1 NOVEL AROMATIC AMIDES, METHOD FOR PREPARING AND COMPOSITIONS CONTAINING SAME, AND USE THEREOF AS PESTICIDES Hoechst Schering AgrEvo S.A. (FR) 1997-11-12 EP claimed
WO-1996022965-A1 NOVEL AROMATIC AMIDES, METHOD FOR PREPARING AND COMPOSITIONS CONTAINING SAME, AND USE THEREOF AS PESTICIDES HOECHST SCHERING AGREVO S.A. (FR) 1996-08-01 WO claimed
US-6013837-A E.G.,4-(2-(3,4,5-TRICHLORO PHENYL) 1-FLUOROCYCLOPROPYL)-N-(2-METHYL PHENYL)BENZAMIDE; PARTICULAR USE AGAINST ARTHROPODS, HELMINTHS AND MOLLUSCS; INSECTICIDES; ACARICIDES; NEMATICIDES; PHOTOSTABILITY; NONTOXIC TO MAMMALS HOECHST MARION ROUSSEL (FR) 2000-01-11 US disclosed