Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | HTR1F | P30939 | 1/20 | 0.39 |
| ▸ | CASP3 | P42574 | 1/20 | 0.37 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.37 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.37 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.37 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 5/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.35 |
| ▸ | RELA | Q04206 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8038471 | 0.87 | NPC1 (0.46) | MAPTRAB9AMEN1KMT2ANPC1 | |
| SCHEMBL8042055 | 0.84 | S1PR4 (0.40) | KDM4E | |
| SCHEMBL8463177 | 0.81 | ALDH1A1 (0.36) | MAPTHTR1FRAB9AMEN1KMT2A | |
| SCHEMBL8057744 | 0.75 | ALDH1A1 (0.36) | MAPTRAB9AMEN1KMT2ANPC1 | |
| SCHEMBL8034546 | 0.75 | RXRA (0.36) | TDP1 | |
| SCHEMBL8036387 | 0.73 | — | — | |
| SCHEMBL8057747 | 0.73 | LMNA (0.49) | MAPTRAB9AMEN1KMT2ANPC1 | |
| SCHEMBL8040665 | 0.73 | POLB (0.56) | RAB9AMEN1KMT2ANPC1ALDH1A1 | |
| SCHEMBL8038470 | 0.72 | POLB (0.48) | MAPTRAB9AMEN1KMT2ANPC1 | |
| SCHEMBL8024723 | 0.71 | ALOX15 (0.36) | LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0915831-A1 | NOVEL METHOD FOR PREPARING AROMATIC AMIDES AND INTERMEDIATES THEREFOR | Hoechst Schering AgrEvo S.A. (FR) | 1999-05-19 | — | — | EP | disclosed |
| WO-1998003470-A1 | NOVEL METHOD FOR PREPARING AROMATIC AMIDES AND INTERMEDIATES THEREFOR | HOECHST SCHERING AGREVO S.A. (FR) | 1998-01-29 | — | — | WO | disclosed |