Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 7/20 | 0.71 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.71 |
| ▸ | TSHR | P16473 | 1/20 | 0.70 |
| ▸ | METAP2 | P50579 | 1/20 | 0.68 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.65 |
| ▸ | GAA | P10253 | 2/20 | 0.65 |
| ▸ | LMNA | P02545 | 1/20 | 0.65 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.65 |
| ▸ | APEX1 | P27695 | 1/20 | 0.64 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.63 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.63 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.63 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.63 |
| ▸ | POLB | P06746 | 1/20 | 0.60 |
| ▸ | HTT | P42858 | 1/20 | 0.60 |
| ▸ | TP53 | P04637 | 1/20 | 0.59 |
| ▸ | GLA | P06280 | 1/20 | 0.59 |
| ▸ | NSD2 | O96028 | 2/20 | 0.58 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.58 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11901003 | 0.87 | KMT2A (0.89) | HPGDKMT2ATSHRMETAP2GAA | |
| SCHEMBL31680569 | 0.87 | KMT2A (0.89) | HPGDKMT2ATSHRMETAP2GAA | |
| SCHEMBL1974245 | 0.83 | NLRP3 (0.80) | HPGDTSHRNLRP3GAALMNA | |
| SCHEMBL28710986 | 0.82 | KMT2A (0.62) | HPGDKMT2ATSHRNLRP3GAA | |
| SCHEMBL8635709 | 0.81 | KMT2A (1.00) | HPGDKMT2AMETAP2GAALMNA | |
| SCHEMBL1984940 | 0.81 | KMT2A (1.00) | HPGDKMT2AMETAP2GAALMNA | |
| SCHEMBL29676833 | 0.81 | HPGD (0.68) | HPGDKMT2ATSHRGAALMNA | |
| SCHEMBL22717260 | 0.81 | HPGD (0.68) | HPGDKMT2ATSHRGAALMNA | |
| SCHEMBL10518947 | 0.81 | METAP2 (1.00) | HPGDKMT2AMETAP2GAALMNA | |
| SCHEMBL1979028 | 0.80 | KMT2A (0.71) | HPGDKMT2ATSHRMETAP2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0751123-B1 | Method for producing alkylsulfinylbenzamides | SUMITOMO SEIKA CHEMICALS (JP) | 2000-05-10 | — | — | EP | claimed |
| US-5672751-A | TREATMENT OF A HALOBENZAMIDE WITH AN ALKANETHIOL IN THE PRESENCE OF A PHASE TRANSFER CATALYST | SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) | 1997-09-30 | — | — | US | claimed |
| EP-0751123-A2 | Method for producing alkylsulfinylbenzamides | SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) | 1997-01-02 | — | — | EP | claimed |
| EP-0657438-A2 | Method for producing alkylsulfinylbenzamides and 1,2-benzisothiazol-3-ones | SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) | 1995-06-14 | — | — | EP | claimed |
| EP-0751123-B1 | Method for producing alkylsulfinylbenzamides | SUMITOMO SEIKA CHEMICALS (JP) | 2000-05-10 | — | — | EP | disclosed |
| US-5744609-A | REACTING AN ALKYLTHIOBENZAMIDE WITH A HALOGEN IN A HETEROGENOUS SOLVENT TO GIVE ALKYLSULFURYLBENZAMIDES INTERMEDIATES; USEFUL ANTIBACTERIAL AND ANTIFUNGAL AGENT | SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) | 1998-04-28 | — | — | US | disclosed |
| US-5672751-A | TREATMENT OF A HALOBENZAMIDE WITH AN ALKANETHIOL IN THE PRESENCE OF A PHASE TRANSFER CATALYST | SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) | 1997-09-30 | — | — | US | disclosed |
| EP-0751123-A2 | Method for producing alkylsulfinylbenzamides | SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) | 1997-01-02 | — | — | EP | disclosed |
| US-5508416-A | HALOGENATING A 2-(ALKYLTHIO)BENZAMIDE, CYCLIZATION TO HETERO RING AND N-S LINKAGE | SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) | 1996-04-16 | — | — | US | disclosed |
| EP-0657438-A2 | Method for producing alkylsulfinylbenzamides and 1,2-benzisothiazol-3-ones | SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) | 1995-06-14 | — | — | EP | disclosed |