Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | CES2 | O00748 | 2/20 | 0.42 |
| ▸ | CES1 | P23141 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | EGFR | P00533 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | FAAH | O00519 | 1/20 | 0.40 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.39 |
| ▸ | TUBB | P07437 | 2/20 | 0.39 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.39 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.39 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.39 |
| ▸ | TUBB4B | P68371 | 2/20 | 0.39 |
| ▸ | TUBB3 | Q13509 | 2/20 | 0.39 |
| ▸ | TUBB2A | Q13885 | 2/20 | 0.39 |
| ▸ | TUBB8 | Q3ZCM7 | 2/20 | 0.39 |
| ▸ | TUBA3E | Q6PEY2 | 2/20 | 0.39 |
| ▸ | TUBA1A | Q71U36 | 2/20 | 0.39 |
| ▸ | TUBA1C | Q9BQE3 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2219978 | 0.94 | SOAT2 (0.49) | TDP1LMNACES1ALDH1A1EPHX2 | |
| SCHEMBL28502354 | 0.80 | EGFR (0.48) | TDP1LMNACES2CES1ALDH1A1 | |
| SCHEMBL3777162 | 0.77 | FAAH (0.59) | TDP1CES2CES1ALDH1A1FAAH | |
| SCHEMBL3787603 | 0.77 | FAAH (0.59) | TDP1CES2CES1ALDH1A1FAAH | |
| SCHEMBL9435633 | 0.77 | FAAH (0.59) | TDP1CES2CES1ALDH1A1FAAH | |
| SCHEMBL3777756 | 0.77 | FAAH (0.59) | TDP1CES2CES1ALDH1A1FAAH | |
| SCHEMBL3778978 | 0.77 | FAAH (0.59) | TDP1CES2CES1ALDH1A1FAAH | |
| SCHEMBL2219057 | 0.74 | TDP1 (0.47) | TDP1LMNAEGFRTUBB4ATUBB | |
| SCHEMBL2215035 | 0.74 | TDP1 (0.47) | TDP1LMNAEGFRTUBB4ATUBB | |
| SCHEMBL2216980 | 0.74 | TDP1 (0.47) | TDP1LMNAEGFRTUBB4ATUBB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0686046-B1 | CONTRAST AGENTS | NYCOMED IMAGING AS (NO) | 2000-05-24 | — | — | EP | disclosed |
| US-5767299-A | Contrast agents | NYCOMED IMAGING AS (NO) | 1998-06-16 | — | — | US | disclosed |
| EP-0686046-A1 | CONTRAST AGENTS | NYCOMED IMAGING AS (NO) | 1995-12-13 | — | — | EP | disclosed |
| WO-1994019025-A2 | CONTRAST AGENTS | NYCOMED IMAGING AS (NO) | 1994-09-01 | — | — | WO | disclosed |