Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 2/20 | 0.67 |
| ▸ | DRD4 | P21917 | 2/20 | 0.67 |
| ▸ | ATM | Q13315 | 1/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.59 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.58 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.58 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.57 |
| ▸ | DRD3 | P35462 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11360462 | 0.91 | DRD2 (0.56) | DRD2DRD4ATMKDM4EALDH1A1 | |
| SCHEMBL11355780 | 0.88 | ATM (0.59) | DRD2DRD4ATMKDM4EALDH1A1 | |
| SCHEMBL11357355 | 0.88 | ATM (0.59) | DRD2DRD4ATMKDM4EALDH1A1 | |
| SCHEMBL8054995 | 0.85 | ADRB2 (0.58) | KDM4EALDH1A1KMT2AADRB2ADRB1 | |
| SCHEMBL9808650 | 0.84 | ADRB2 (0.63) | KDM4EALDH1A1KMT2AADRB2ADRB1 | |
| Tolamolol SCHEMBL611643 | 0.83 | ATM (0.59) | ATMKDM4EALDH1A1KMT2AADRB2 | |
| Tolamolol SCHEMBL613511 | 0.83 | ATM (0.59) | ATMKDM4EALDH1A1KMT2AADRB2 | |
| SCHEMBL10740739 | 0.82 | ADRB2 (0.65) | KDM4EALDH1A1KMT2AADRB2ADRB1 | |
| SCHEMBL11360960 | 0.82 | KDM4E (0.58) | KDM4EALDH1A1KMT2AADRB2ADRB1 | |
| SCHEMBL11364907 | 0.82 | ADRB2 (0.66) | DRD2DRD4KDM4EKMT2AADRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6051605-A | TREATING PSYCHOSIS AND SCHIZOPHRENIA USING A COMPOUND THAT IS AN ANTAGONIST OF DOPAMINE D4 RECEPTORS | WARNER-LAMBERT COMPANY (US) | 2000-04-18 | — | — | US | disclosed |