Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.38 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | RBP4 | P02753 | 1/20 | 0.32 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.32 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.32 |
| ▸ | CTSS | P25774 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30706305 | 1.00 | CA2 (0.43) | CA2ALDH1A1ALOX15GABRA1GABRB2 | |
| SCHEMBL9060838 | 0.88 | ALDH1A1 (0.45) | CA2ALDH1A1ALOX15TSHR | |
| SCHEMBL29263958 | 0.84 | CA2 (0.46) | CA2ALDH1A1ALOX15GABRA1GABRB2 | |
| SCHEMBL29678146 | 0.82 | ALOX15 (0.47) | CA2ALDH1A1ALOX15GABRA1GABRB2 | |
| SCHEMBL1434698 | 0.82 | CA2 (0.45) | CA2ALDH1A1ALOX15GABRA1GABRB2 | |
| SCHEMBL273494 | 0.82 | ALOX15 (0.47) | CA2ALDH1A1ALOX15GABRA1GABRB2 | |
| SCHEMBL2154401 | 0.82 | ALDH1A1 (0.48) | CA2ALDH1A1ALOX15GABRA1GABRB2 | |
| SCHEMBL28774188 | 0.81 | CA2 (0.43) | CA2ALDH1A1ALOX15GABRA1GABRB2 | |
| SCHEMBL28819980 | 0.81 | CA2 (0.43) | CA2ALDH1A1GABRA1GABRB2TDP1 | |
| SCHEMBL27764801 | 0.81 | ALOX15 (0.46) | CA2ALDH1A1ALOX15GABRA1GABRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104603105-A | Carboxamide or sulfonamide substituted nitrogen-containing 5-membered heterocycles as modulators for the orphan nuclear receptor ROR Gamma | PHENEX PHARMACEUTICALS AG | 2015-05-06 | — | — | CN | disclosed |
| EP-0999211-A1 | NOVEL PURINE DERIVATIVES AND MEDICINAL USE THEREOF | JAPAN ENERGY CORPORATION (JP) | 2000-05-10 | — | — | EP | disclosed |
| CN-1016169-B | PROCESS FOR PREPARING IMIDAZOLE DERIVATIVES | HOFFMANN LA ROCHE (CH) | 1992-04-08 | — | — | CN | disclosed |
| CN-88101452-A | Imdazole derivatives | — | 1988-10-05 | — | — | CN | disclosed |