Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EP300 | Q09472 | 1/20 | 0.39 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.38 |
| ▸ | USP7 | Q93009 | 3/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.35 |
| ▸ | GPR4 | P46093 | 1/20 | 0.35 |
| ▸ | HTR3A | P46098 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.34 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.34 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.34 |
| ▸ | FAAH | O00519 | 2/20 | 0.34 |
| ▸ | CASP6 | P55212 | 1/20 | 0.34 |
| ▸ | MPO | P05164 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.33 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL187243 | 0.86 | FAAH (0.43) | NR1H4HTR3AFAAHHTR2CGABRA1 | |
| SCHEMBL3098625 | 0.76 | GABRA1 (0.47) | NR1H4HTR3AFAAHHTR2CGABRA1 | |
| SCHEMBL15006790 | 0.72 | GABRA1 (0.37) | NR1H4TLR9TLR8TLR7MPO | |
| SCHEMBL4419637 | 0.71 | NR1H4 (0.65) | NR1H4USP7TLR9TLR8TLR7 | |
| SCHEMBL3088777 | 0.71 | FAAH (0.47) | HTR3AFAAHHTR2CGABRA1GABRB2 | |
| SCHEMBL3099656 | 0.70 | HTR2C (0.48) | EP300NR1H4FAAHHTR2CMEN1 | |
| SCHEMBL187612 | 0.70 | NR4A2 (0.51) | NR1H4KCNH2SIGMAR1HTR2CGABRA1 | |
| SCHEMBL3097379 | 0.69 | HTR2A (0.45) | FAAHHTR2CMEN1KMT2AGABRA1 | |
| SCHEMBL3099648 | 0.69 | HTR2A (0.45) | FAAHHTR2CMEN1KMT2AGABRA1 | |
| SCHEMBL7964498 | 0.69 | MPO (0.49) | NR1H4TLR9TLR7MPOMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009050248-A1 | SUBSTITUTED PIPERIDINO-DIHYDROTHIENOPYRIMIDINES | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2009-04-23 | — | — | WO | disclosed |